Table 1. Clinical and laboratory data in... | American Society of Hematology

Table 1.

Clinical and laboratory data in patients with multiple myeloma with and without 13q14 deletion

Variable^*	13q14 Deleted (n = 46)	Normal 13q14 (n = 51)	P Value
Age, y	65.3	65.2	.95
Sex, % male/% female	35.6/64.4	35.8/64.2	.97
Stage of MM at diagnosis, % of patients
I or II	27.1	49.1
III	72.9	50.9	.022
Paraprotein, % of patients
IgA	22.9	27.3
Non-IgA	77.1	72.7	.62
Percentage of bone marrow plasma cells	37	29	.085
Intermediate and high-grade morphologic features, % of patients	29.6	15.7	.10
Creatinine (μmol/L)	136	111	.18
Hemoglobin (g/L)	104	113	.10
Platelets (×10⁹/L)	183	204	.26
β₂-Microglobulin (mg/L)	6.7	3.6	.059
C-reactive protein (mg/L)	30	16	.27
Lactate dehydrogenase (U/L)	203	181	.27
Deletion of 17p13, % of patients	38.6	11.5	.002
Ki-67, % of positive cells^†	22.0	15.6	.0008
Response to induction chemotherapy, % of patients^‡	40.8	78.6	.009

Variable^*	13q14 Deleted (n = 46)	Normal 13q14 (n = 51)	P Value
Age, y	65.3	65.2	.95
Sex, % male/% female	35.6/64.4	35.8/64.2	.97
Stage of MM at diagnosis, % of patients
I or II	27.1	49.1
III	72.9	50.9	.022
Paraprotein, % of patients
IgA	22.9	27.3
Non-IgA	77.1	72.7	.62
Percentage of bone marrow plasma cells	37	29	.085
Intermediate and high-grade morphologic features, % of patients	29.6	15.7	.10
Creatinine (μmol/L)	136	111	.18
Hemoglobin (g/L)	104	113	.10
Platelets (×10⁹/L)	183	204	.26
β₂-Microglobulin (mg/L)	6.7	3.6	.059
C-reactive protein (mg/L)	30	16	.27
Lactate dehydrogenase (U/L)	203	181	.27
Deletion of 17p13, % of patients	38.6	11.5	.002
Ki-67, % of positive cells^†	22.0	15.6	.0008
Response to induction chemotherapy, % of patients^‡	40.8	78.6	.009

Median values are given for quantitative variables.

Determined in 74 patients.

Conventional dose chemotherapy, applicable to 81 patients.