p16(INK4A) Southern and PCR results for 17 adult patients with ALL
Patient . | Southern analyses (deletion [D] or rearrangement [R]) . | PCR analyses . |
---|---|---|
1 | D3-150 | Absent (exon 1 only) |
2 | D | Absent (exons 1 + 2) |
3 | D | Absent (exons 1 + 2) |
4 | D | Absent (exons 1 + 2) |
5 | D | Absent (exons 1 + 2) |
6 | D | Absent (exons 1 + 2) |
7 | R | Absent (exon 2 only) |
8 | R | Absent (exons 1 + 2) |
9 | D | Absent (exons 1 + 2) |
10 | R | Present |
11 | D | Present |
12 | D | N/A |
13 | D | N/A |
14 | N/A | Absent (exons 1 + 2) |
15 | N/A | Absent (exons 1 + 2) |
16 | N/A | Absent (exons 1 + 2) |
17 | N/A | Absent (exons 1 + 2) |
Patient . | Southern analyses (deletion [D] or rearrangement [R]) . | PCR analyses . |
---|---|---|
1 | D3-150 | Absent (exon 1 only) |
2 | D | Absent (exons 1 + 2) |
3 | D | Absent (exons 1 + 2) |
4 | D | Absent (exons 1 + 2) |
5 | D | Absent (exons 1 + 2) |
6 | D | Absent (exons 1 + 2) |
7 | R | Absent (exon 2 only) |
8 | R | Absent (exons 1 + 2) |
9 | D | Absent (exons 1 + 2) |
10 | R | Present |
11 | D | Present |
12 | D | N/A |
13 | D | N/A |
14 | N/A | Absent (exons 1 + 2) |
15 | N/A | Absent (exons 1 + 2) |
16 | N/A | Absent (exons 1 + 2) |
17 | N/A | Absent (exons 1 + 2) |
Results of Southern analyses and PCR for detection of p16(INK4A) in specimens from each of 17 adult patients with ALL with p16 aberrations.
In every patient except patient 1, p16(INK4A) deletions also involved the p15(INK4B) gene.
N/A = not available.