Table 6.

p16 Expression in three differentiation compartments6-150

Group CD34+lin− CD34+lin+ CD34−lin+
p16 Normal 95% (50-100)  83% (30-100)  100% (30-100) 
 (n = 9)  (n = 4)  (n = 3) 
p16 Abnormal  10% (0-50)  20% (0-50)  65% (20-100) 
 (n = 5)  (n = 7) (n = 3) 
Group CD34+lin− CD34+lin+ CD34−lin+
p16 Normal 95% (50-100)  83% (30-100)  100% (30-100) 
 (n = 9)  (n = 4)  (n = 3) 
p16 Abnormal  10% (0-50)  20% (0-50)  65% (20-100) 
 (n = 5)  (n = 7) (n = 3) 
F6-150

Bone marrow cells from 16 patients were sorted into three differentiation compartments as described in “Materials and methods.” Cells in each compartment were examined for p16(INK4A) expression by immunocytochemical staining. Results are median percentages of p16-positive cells in each compartment with ranges in parentheses.

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