p16(INK4A) Expression in sorted bone marrow compartments of patients with p16(INK4A) abnormalities7-150
Patient . | CD34+lin− . | CD34+lin+ . | CD34−lin+ . |
---|---|---|---|
10 | insuff. | 0 (5000) | N/A |
117-150 | 0 (100)7-151 | 50 (3000) | N/A |
127-150 | 0 (100) | 0 (2000) | N/A |
13 | 50 (50) | 50 (1000) | N/A |
14 | insuff. | 20 (1000) | 20 (130) |
15 | 10 (1000) | 50 (5600) | 65 (2000) |
167-150 | 50 (75) | 15 (3000) | 100 (190) |
Patient . | CD34+lin− . | CD34+lin+ . | CD34−lin+ . |
---|---|---|---|
10 | insuff. | 0 (5000) | N/A |
117-150 | 0 (100)7-151 | 50 (3000) | N/A |
127-150 | 0 (100) | 0 (2000) | N/A |
13 | 50 (50) | 50 (1000) | N/A |
14 | insuff. | 20 (1000) | 20 (130) |
15 | 10 (1000) | 50 (5600) | 65 (2000) |
167-150 | 50 (75) | 15 (3000) | 100 (190) |
Bone marrows were sorted into 3 differentiation compartments as described in “Materials and methods.” Cells in each compartment were examined for p16(INK4A) expression by immunocytochemical staining. Results are percentages of p16-positive cells detected in each compartment.
Patients in which lymphoblasts did not express CD34.
N/A, not available; insuff., insufficient cells sorted into the CD34+lin− compartment for analysis.
Numbers in parentheses indicate number of cells sorted per slide. On slides with less than 100 cells, all cells were counted.