Table 2.

CTLp and HTLp frequencies of IUT patients against 1 or more IUT donors

Recipient No. IUTs {IUT tested}CTLp/1 × 106HTLp/1 × 106
Donor (+FK18) 3dp (+FK18) Donor 3dp
2 {2}  49 (14)  58 (20)  73  31 
2  3 {1}  370 (38)  162 (28)  1475 171  
3  3 {1}  141 (25)  138 (15)* 127  194  
 3 {2}  40 (6) 64 (12)  180  215  
4  2 {2}  71* 99* 175  886  
5  2 {1} 417 (20)  88 (7)* 969  357  
1 {1}  32 (2)  43 (4)  621  499 
7  4 {2}  134 (28)  140 (19)* 350 110  
8  4 {1}  226 (20)  82 (11) 40  64  
9  1 {1}  38 (0) 111 (15)  566  1175 
Recipient No. IUTs {IUT tested}CTLp/1 × 106HTLp/1 × 106
Donor (+FK18) 3dp (+FK18) Donor 3dp
2 {2}  49 (14)  58 (20)  73  31 
2  3 {1}  370 (38)  162 (28)  1475 171  
3  3 {1}  141 (25)  138 (15)* 127  194  
 3 {2}  40 (6) 64 (12)  180  215  
4  2 {2}  71* 99* 175  886  
5  2 {1} 417 (20)  88 (7)* 969  357  
1 {1}  32 (2)  43 (4)  621  499 
7  4 {2}  134 (28)  140 (19)* 350 110  
8  4 {1}  226 (20)  82 (11) 40  64  
9  1 {1}  38 (0) 111 (15)  566  1175 

Precursor frequencies are displayed as number of precursors per 1 × 106 nucleated cells. No IUTs refers to the total number of IUTs; number between brackets ({ }) refers to the specific IUT donor tested. CTLp frequencies determined after addition of anti-CD8 antibody (FK 18) to effector cells are displayed in parentheses.

*

Frequencies with a goodness of fit > 15. 3dp, third-party controls.

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