Prognostic stratification at initial diagnosis and at time of splenectomy and its influence on time to splenectomy and survival in 223 patients with MMM
Dupriez score* . | No.of patients . | Median time to splenectomy, mo . | P value . | Median survival after diagnosis, mo . | P value . | Median survival after splenectomy, mo . | P value . |
---|---|---|---|---|---|---|---|
At diagnosis | |||||||
0 | 95 | 30 | 90 | 26 | |||
1 | 88 | 24 | 66 | 22 | |||
2 | 36 | 11 | < .01 | 62 | .41 | 24 | .90 |
Total | 219 | ||||||
At splenectomy | |||||||
0 | 51 | NA | 99 | 26 | |||
1 | 109 | NA | 69 | 24 | |||
2 | 62 | NA | 62 | 0.61 | 26 | .86 | |
Total | 222 |
Dupriez score* . | No.of patients . | Median time to splenectomy, mo . | P value . | Median survival after diagnosis, mo . | P value . | Median survival after splenectomy, mo . | P value . |
---|---|---|---|---|---|---|---|
At diagnosis | |||||||
0 | 95 | 30 | 90 | 26 | |||
1 | 88 | 24 | 66 | 22 | |||
2 | 36 | 11 | < .01 | 62 | .41 | 24 | .90 |
Total | 219 | ||||||
At splenectomy | |||||||
0 | 51 | NA | 99 | 26 | |||
1 | 109 | NA | 69 | 24 | |||
2 | 62 | NA | 62 | 0.61 | 26 | .86 | |
Total | 222 |
NA indicates not applicable.
A Dupriez score of 0 was assigned for a hemoglobin level greater than 100 g/L and a white blood cell count between 4 × 109/L and 30 × 109/L, a score of 1 for either a hemoglobin level less than 100 g/L or a white blood cell count greater than 30 × 109/L or less than 4 × 109/L, and a score of 2 if both the hemoglobin level and white blood cell count were in the aberrant ranges.