Table 6. Differentiation potential of... | American Society of Hematology

Table 6.

Differentiation potential of the cells within single BFU-E–derived colonies transplanted at day 5 in secondary cultures stimulated with either EPO or TPO

	Secondary Growth
	EPO			TPO
	Wells Positive for Growth	CFU-E/Well (SEM)	Single Mk-Cells/Well (SEM)	Wells Positive for Growth	CFU-E/Well (SEM)	Single Mk-Cells/Well (SEM)
Single BFU-E–derived colonies (n = 24)^6-150	22 (92%)	1-17 (5 ± 3)	0-6 (3 ± 2)	22 (92%)	0 (−)	5-37 (22 ± 9)
Single GM colonies (n = 12)	0	0	0	2^6-151 (17%)	0	0

	Secondary Growth
	EPO			TPO
	Wells Positive for Growth	CFU-E/Well (SEM)	Single Mk-Cells/Well (SEM)	Wells Positive for Growth	CFU-E/Well (SEM)	Single Mk-Cells/Well (SEM)
Single BFU-E–derived colonies (n = 24)^6-150	22 (92%)	1-17 (5 ± 3)	0-6 (3 ± 2)	22 (92%)	0 (−)	5-37 (22 ± 9)
Single GM colonies (n = 12)	0	0	0	2^6-151 (17%)	0	0

BFU-E = burst-forming unit erythroid; CFU-E = colony-forming unit-erythroid; EPO = erythropoietin; GM = granulocyte macrophage; TPO = thrombopoietin.

F6-150

The minimum and maximum number of CFU-E and megakaryocytes (Mk) detected per well.

F6-151

Small clusters of macrophage-like cells.

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