Cytokine production by alloantigen-specific CD4+ CTL clones
| Donor . | Effector . | Stimulator . | Cytokine production (pg/mL)3-150 . | ||
|---|---|---|---|---|---|
| IL-4 . | IL-10 . | IFN-γ . | |||
| M.Y. | CD4+ clone #1-1 | Auto LCL | 0 | 44 | 135 |
| Fas+/− LCL | 118 | 3,492 | 1,812 | ||
| CD4+ clone #1-2 | Auto LCL | 0 | 103 | 274 | |
| Fas+/− LCL | 123 | 3,684 | 1,952 | ||
| CD4+ clone #3-1 | Auto LCL | 0 | 133 | 209 | |
| Fas−/− LCL | 0 | 3,812 | 1,924 | ||
| CD4+ clone 3-2 | Auto LCL | 0 | 84 | 183 | |
| Fas−/− LCL | 156 | 3,060 | 2,224 | ||
| H.O. | CD4+ clone #5-1 | Auto LCL | 0 | 172 | 85 |
| Fas+/− LCL | 118 | 3,260 | 2,048 | ||
| CD4+ clone #5-2 | Auto LCL | 0 | 131 | 284 | |
| Fas+/− LCL | 123 | 3,668 | 2,096 | ||
| CD4+ clone #7-1 | Auto LCL | 0 | 181 | 302 | |
| Fas−/− LCL | 0 | 3,700 | 2,068 | ||
| CD4+ clone #7-2 | Auto LCL | 0 | 238 | 160 | |
| Fas−/− LCL | 157 | 3,760 | 1,696 | ||
| Donor . | Effector . | Stimulator . | Cytokine production (pg/mL)3-150 . | ||
|---|---|---|---|---|---|
| IL-4 . | IL-10 . | IFN-γ . | |||
| M.Y. | CD4+ clone #1-1 | Auto LCL | 0 | 44 | 135 |
| Fas+/− LCL | 118 | 3,492 | 1,812 | ||
| CD4+ clone #1-2 | Auto LCL | 0 | 103 | 274 | |
| Fas+/− LCL | 123 | 3,684 | 1,952 | ||
| CD4+ clone #3-1 | Auto LCL | 0 | 133 | 209 | |
| Fas−/− LCL | 0 | 3,812 | 1,924 | ||
| CD4+ clone 3-2 | Auto LCL | 0 | 84 | 183 | |
| Fas−/− LCL | 156 | 3,060 | 2,224 | ||
| H.O. | CD4+ clone #5-1 | Auto LCL | 0 | 172 | 85 |
| Fas+/− LCL | 118 | 3,260 | 2,048 | ||
| CD4+ clone #5-2 | Auto LCL | 0 | 131 | 284 | |
| Fas+/− LCL | 123 | 3,668 | 2,096 | ||
| CD4+ clone #7-1 | Auto LCL | 0 | 181 | 302 | |
| Fas−/− LCL | 0 | 3,700 | 2,068 | ||
| CD4+ clone #7-2 | Auto LCL | 0 | 238 | 160 | |
| Fas−/− LCL | 157 | 3,760 | 1,696 | ||
The CD4+ clone cells were cultured with or without allogeneic LCL for 72 hours, and the concentration of each cytokine in the culture supernatant was determined by ELISA.