Properties of the platelet F11 receptor obtained by analysis of its amino acid composition deduced from the F11R cDNA sequence
Properties . | Amino Acids . |
---|---|
Molecular weight | 29.682 kd |
Isoelectric point | 6.72 |
Transmembrane helices | 12-29 (inside → outside) |
239-258 (outside → inside) | |
Cleavable N-term signal sequence | 1-27 |
Cytoplasmic tail | 255-299 |
N-glycosylation site | Asn-185 |
cAMP- or cGMP-dependent protein kinase phosphorylation site | Thr-273 |
PKC phosphorylation sites | Ser-57 Thr-269 |
Thr-69 Ser-274 | |
Thr-95 Ser-275 | |
Ser-179 Ser-284 | |
Casein kinase II phosphorylation sites | Ser-34 Ser-154 |
Ser-82 Thr-193 | |
Thr-100 Ser-203 | |
Ser-118 Ser-287 | |
Thr-152 | |
Tyrosines in the cytoplasmic tail | Tyr-260 Tyr-279 |
Properties . | Amino Acids . |
---|---|
Molecular weight | 29.682 kd |
Isoelectric point | 6.72 |
Transmembrane helices | 12-29 (inside → outside) |
239-258 (outside → inside) | |
Cleavable N-term signal sequence | 1-27 |
Cytoplasmic tail | 255-299 |
N-glycosylation site | Asn-185 |
cAMP- or cGMP-dependent protein kinase phosphorylation site | Thr-273 |
PKC phosphorylation sites | Ser-57 Thr-269 |
Thr-69 Ser-274 | |
Thr-95 Ser-275 | |
Ser-179 Ser-284 | |
Casein kinase II phosphorylation sites | Ser-34 Ser-154 |
Ser-82 Thr-193 | |
Thr-100 Ser-203 | |
Ser-118 Ser-287 | |
Thr-152 | |
Tyrosines in the cytoplasmic tail | Tyr-260 Tyr-279 |