Plasma factor VIII activity in skin graft recipient mice
| . | Week . | 2 . | 4 . | 6 . | 8 . |
|---|---|---|---|---|---|
| Mouse | |||||
| A | 5% | 12% | 20% | 3%* | |
| B | < 1% | < 1% | 5% | 4% | |
| Control | < 1% | ————————————————————→ | |||
| . | Week . | 2 . | 4 . | 6 . | 8 . |
|---|---|---|---|---|---|
| Mouse | |||||
| A | 5% | 12% | 20% | 3%* | |
| B | < 1% | < 1% | 5% | 4% | |
| Control | < 1% | ————————————————————→ | |||
Values represent levels of plasma factor VIII activity compared with normal mice as determined using the COAMATIC assay.
Mouse A was killed 8 weeks after grafting when it appeared ill after bleeding from the rectal area. Similarly, mouse B was killed 12 weeks after grafting when it appeared ill. Diminished factor VIII activity was observed then, although no clear cause of illness was evident. Blood was not obtained at the 10-week point from this mouse.