Table 5.

Comparison of V1-69 CDR3 sequences

SG-MALT4-150CLL4-151
Length  13.9 ± 1.5 19.0 ± 3.5  
JH4  15/17 (88%)  1/26 (4%)  
JH6 0/17  12/26 (46%)  
1st AA-E  10/17 (59%) 1/26 (4%)  
5′J AA-P  8/17 (47%)  0/26 
SG-MALT4-150CLL4-151
Length  13.9 ± 1.5 19.0 ± 3.5  
JH4  15/17 (88%)  1/26 (4%)  
JH6 0/17  12/26 (46%)  
1st AA-E  10/17 (59%) 1/26 (4%)  
5′J AA-P  8/17 (47%)  0/26 

SG-MALT = salivary gland mucosa-associated lymphoid tissue; CLL = chronic lymphocytic leukemia.

F4-150

SG-MALT data from this and previous studies.4 5 1st AA-E refers to the first amino acid at V-D junction being glutamate (E), whereas 5′J AA-P refers to a proline being immediately 5′ to the J segment start (Figure 2).

F4-151

CLL data from Johnson et al.10 

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