Frequency of Mac-1+Gr-1+-double positive cells in the peripheral blood of mice 7 days after candida infection
| Genotype . | WBC (109/L)3-150 . | % Cell type . | |
|---|---|---|---|
| Mac-1+Gr-1med . | Mac-1+Gr-1hi . | ||
| Wild-type | 8.4 ± 0.8 | 36.0 ± 7.0 | 14.0 ± 3.5 |
| G-CSF−/− | 6.6 ± 0.1 | 28.5 ± 5.8 | 4.1 ± 2.03-151 |
| G-CSF−/−/GM-CSF−/− | 5.3 ± 0.9 | 28.0 ± 2.4 | 6.0 ± 3.03-151 |
| G-CSF−/−/IL-6−/− | 6.2 ± 0.4 | 27.0 ± 4.0 | 6.0 ± 3.03-151 |
| Genotype . | WBC (109/L)3-150 . | % Cell type . | |
|---|---|---|---|
| Mac-1+Gr-1med . | Mac-1+Gr-1hi . | ||
| Wild-type | 8.4 ± 0.8 | 36.0 ± 7.0 | 14.0 ± 3.5 |
| G-CSF−/− | 6.6 ± 0.1 | 28.5 ± 5.8 | 4.1 ± 2.03-151 |
| G-CSF−/−/GM-CSF−/− | 5.3 ± 0.9 | 28.0 ± 2.4 | 6.0 ± 3.03-151 |
| G-CSF−/−/IL-6−/− | 6.2 ± 0.4 | 27.0 ± 4.0 | 6.0 ± 3.03-151 |
WBCs were incubated with antibodies against myeloid cell markers (Gr-1 and Mac-1) and analyzed on FACScan using CellQuest software. Data are represented as mean ± SD. Ten to 12 mice of each genotype were analyzed.
Total WBC count as determined by Sysmex-K1000.
P < .05 compared to wild-type mice.
P < .05 compared to wild-type mice.