Clinical characteristics of the study population
| Characteristics . | Frequency n = 541 . | 5 y OS . | 5 y DFS . |
|---|---|---|---|
| LDH | |||
| ≤ Normal | 43% | 73 ± 6% | 61 ± 6% |
| > Normal | 57% | 64 ± 5%* | 56 ± 6%* |
| Stage | |||
| Localized (I-II) | 39% | 76 ± 6% | 66 ± 6% |
| Disseminated (III-IV) | 61% | 63 ± 5%* | 51 ± 6%* |
| Performance status | |||
| 0-1 | 80% | 70 ± 5% | 59 ± 6% |
| 2-4 | 20% | 62 ± 8%† | 53 ± 9% |
| IPI Score | |||
| 0 | 15% | 84 ± 8% | 76 ± 10% |
| 1 | 40% | 70 ± 7% | 58 ± 7% |
| 2 | 35% | 61 ± 8% | 55 ± 8% |
| 3 | 10% | 58 ± 14%* | 47 ± 14%* |
| Consolidative treatment | |||
| Sequential chemotherapy | 50.5% | 67 ± 6% | 54 ± 7% |
| HDT with ASCT | 49.5% | 69 ± 6% | 62 ± 6% |
| Characteristics . | Frequency n = 541 . | 5 y OS . | 5 y DFS . |
|---|---|---|---|
| LDH | |||
| ≤ Normal | 43% | 73 ± 6% | 61 ± 6% |
| > Normal | 57% | 64 ± 5%* | 56 ± 6%* |
| Stage | |||
| Localized (I-II) | 39% | 76 ± 6% | 66 ± 6% |
| Disseminated (III-IV) | 61% | 63 ± 5%* | 51 ± 6%* |
| Performance status | |||
| 0-1 | 80% | 70 ± 5% | 59 ± 6% |
| 2-4 | 20% | 62 ± 8%† | 53 ± 9% |
| IPI Score | |||
| 0 | 15% | 84 ± 8% | 76 ± 10% |
| 1 | 40% | 70 ± 7% | 58 ± 7% |
| 2 | 35% | 61 ± 8% | 55 ± 8% |
| 3 | 10% | 58 ± 14%* | 47 ± 14%* |
| Consolidative treatment | |||
| Sequential chemotherapy | 50.5% | 67 ± 6% | 54 ± 7% |
| HDT with ASCT | 49.5% | 69 ± 6% | 62 ± 6% |