Techniques of T-cell depletion
| Group . | Technique of T-cell depletion . |
|---|---|
| Narrow-specificity antibodies N = 450 (52%) | Antibodies targeting T10B9 (α/β T-cell receptor), CD3 ± CD7, CD3 + CD6 + CD8, CD4 ± CD8, CD4 + CD5 + CD8, CD5 ± CD8, CD6 ± CD7, CD6 + CD8, CD6 + CD7 + CD8, CD8 ± CD7 |
| Broad-specificity antibodies N = 73 (8%) | Antibodies targeting CD2 ± CD3, CD2 + CD5, CD2 + CD7, CD2 + CD8, CD2 + CD4 + CD8, CD2 + CD5 + CD7, CD2 + CD5 + CD8, CD2 + CD3 + CD4 + CD8, CD2 + CD3 + CD4 + CD5 + CD6 + CD8 + CD28; ATG incubation |
| Campath 1 N = 131 (15%) | Antibodies targeting CD52 including Campath 1G (IgG-2b), Campath 1M (IgM) |
| Elutriation N = 75 (9%) | Elutriation; density-gradient centrifugation (DGR) |
| Lectins/SRBC N = 141 (16%) | Lectins + CD5 + CD8; lectins ± sheep red blood cell; rosetting (SRBC); SRBC ± DGR |
| Group . | Technique of T-cell depletion . |
|---|---|
| Narrow-specificity antibodies N = 450 (52%) | Antibodies targeting T10B9 (α/β T-cell receptor), CD3 ± CD7, CD3 + CD6 + CD8, CD4 ± CD8, CD4 + CD5 + CD8, CD5 ± CD8, CD6 ± CD7, CD6 + CD8, CD6 + CD7 + CD8, CD8 ± CD7 |
| Broad-specificity antibodies N = 73 (8%) | Antibodies targeting CD2 ± CD3, CD2 + CD5, CD2 + CD7, CD2 + CD8, CD2 + CD4 + CD8, CD2 + CD5 + CD7, CD2 + CD5 + CD8, CD2 + CD3 + CD4 + CD8, CD2 + CD3 + CD4 + CD5 + CD6 + CD8 + CD28; ATG incubation |
| Campath 1 N = 131 (15%) | Antibodies targeting CD52 including Campath 1G (IgG-2b), Campath 1M (IgM) |
| Elutriation N = 75 (9%) | Elutriation; density-gradient centrifugation (DGR) |
| Lectins/SRBC N = 141 (16%) | Lectins + CD5 + CD8; lectins ± sheep red blood cell; rosetting (SRBC); SRBC ± DGR |