Anti-EBV and anti-allo frequencies, including confidence intervals of unsorted, NIT+, and NIT− T cells of 5 donors after gene transfer on day 8
| . | Frequency unsorted . | Confidence interval . | Frequency NIT+ . | Confidence interval . | Frequency NIT− . | Confidence interval . |
|---|---|---|---|---|---|---|
| Donor S.B. | ||||||
| Anti-EBV | 1/9630 | 1/7483-1/13 694 | 1/1577 | 1/1372-1/1854 | 1/13 645 | 1/9327-1/14 163 |
| Anti-allo | 1/9507 | 1/8241-1/11 232 | 1/114 716 | 1/71 118-1/296 446 | 1/12 431 | 1/10 833-1/15 494 |
| Ratio | 1:1 | 72:1 | 1:1 | |||
| Donor U.S. | ||||||
| Anti-EBV | 1/2883 | 1/2396-1/3418 | 1/755 | 1/609-1/1086 | 1/8462 | 1/6245-1/11 479 |
| Anti-allo | 1/14 621 | 1/11 278-1/20 186 | 1/66 773 | 1/48 832-1/118 494 | 1/14 800 | 1/11 978-1/20 465 |
| Ratio | 5:1 | 88:1 | 1.7:1 | |||
| Donor J.A. | ||||||
| Anti-EBV | 1/6116 | 1/5417-1/7021 | 1/4876 | 1/4121-1/5970 | nd | |
| Anti-allo | 1/2995 | 1/2650-1/3443 | 1/45 397 | 1/32 175-1/77 069 | nd | |
| Ratio | 1:2 | 10:1 | ||||
| Donor J.K. | ||||||
| Anti-EBV | 1/9548 | 1/7886-1/12 098 | 1/5728 | 1/4908-1/6879 | 1/14 800 | 1/12 987-1/16 734 |
| Anti-allo | 1/24 770 | 1/18 693-1/37 182 | 1/52 704 | 1/35 668-1/88 366 | 1/11 596 | 1/10 324-1/13 453 |
| Ratio | 2.5:1 | 10:1 | 1:1.2 | |||
| Donor M.A. | ||||||
| Anti-EBV | 1/2692 | 1/1963-1/3106 | 1/738 | 1/584-1/1002 | 1/3623 | 1/3234-1/4119 |
| Anti-allo | 1/17 247 | 1/14 202-1/21 952 | 1/91 024 | 1/59 436-1/194 271 | 1/15 226 | 1/12 770-1/18 850 |
| Ratio | 6:1 | 123:1 | 4:1 |
| . | Frequency unsorted . | Confidence interval . | Frequency NIT+ . | Confidence interval . | Frequency NIT− . | Confidence interval . |
|---|---|---|---|---|---|---|
| Donor S.B. | ||||||
| Anti-EBV | 1/9630 | 1/7483-1/13 694 | 1/1577 | 1/1372-1/1854 | 1/13 645 | 1/9327-1/14 163 |
| Anti-allo | 1/9507 | 1/8241-1/11 232 | 1/114 716 | 1/71 118-1/296 446 | 1/12 431 | 1/10 833-1/15 494 |
| Ratio | 1:1 | 72:1 | 1:1 | |||
| Donor U.S. | ||||||
| Anti-EBV | 1/2883 | 1/2396-1/3418 | 1/755 | 1/609-1/1086 | 1/8462 | 1/6245-1/11 479 |
| Anti-allo | 1/14 621 | 1/11 278-1/20 186 | 1/66 773 | 1/48 832-1/118 494 | 1/14 800 | 1/11 978-1/20 465 |
| Ratio | 5:1 | 88:1 | 1.7:1 | |||
| Donor J.A. | ||||||
| Anti-EBV | 1/6116 | 1/5417-1/7021 | 1/4876 | 1/4121-1/5970 | nd | |
| Anti-allo | 1/2995 | 1/2650-1/3443 | 1/45 397 | 1/32 175-1/77 069 | nd | |
| Ratio | 1:2 | 10:1 | ||||
| Donor J.K. | ||||||
| Anti-EBV | 1/9548 | 1/7886-1/12 098 | 1/5728 | 1/4908-1/6879 | 1/14 800 | 1/12 987-1/16 734 |
| Anti-allo | 1/24 770 | 1/18 693-1/37 182 | 1/52 704 | 1/35 668-1/88 366 | 1/11 596 | 1/10 324-1/13 453 |
| Ratio | 2.5:1 | 10:1 | 1:1.2 | |||
| Donor M.A. | ||||||
| Anti-EBV | 1/2692 | 1/1963-1/3106 | 1/738 | 1/584-1/1002 | 1/3623 | 1/3234-1/4119 |
| Anti-allo | 1/17 247 | 1/14 202-1/21 952 | 1/91 024 | 1/59 436-1/194 271 | 1/15 226 | 1/12 770-1/18 850 |
| Ratio | 6:1 | 123:1 | 4:1 |