Table 3. Expression of TNF-R and TNF-L... | American Society of Hematology

Table 3.

Expression of TNF-R and TNF-L in patients with LDGL after different culture conditions

Patient number	Culture conditions	CD40	CD40L	CD27	CD70	CD30	CD30L	CD95 (Fas)	CD95L (FasL)
Case 1	Medium alone^3-150	+	+	−	+	−	−	+	+
	rIL-2	ns^3-151	ns	ns	19^3-152	ns	ns	ns	ns
	rIL-15	ns	22^3-153	ns	24^3-152	ns	ns	ns	ns
Case 4	Medium alone	+	+	−	+	+	−	+	+
	rIL-2	ns	ns	ns	ns	ns	ns	ns	ns
	rIL-15	ns	ns	ns	ns	29^3-153	ns	ns	ns
Case 17	Medium alone	−	+	−	+	+	−	+	+
	rIL-2	ns	ns	ns	ns	ns	ns	ns	ns
	rIL-15	ns	ns	ns	ns	ns	ns	ns	ns
Case 21	Medium alone	+	+	−	+	−	−	+	−
	rIL-2	ns	ns	ns	ns	ns	ns	ns	ns
	rIL-15	ns	ns	ns	ns	ns	ns	ns	ns

Patient number	Culture conditions	CD40	CD40L	CD27	CD70	CD30	CD30L	CD95 (Fas)	CD95L (FasL)
Case 1	Medium alone^3-150	+	+	−	+	−	−	+	+
	rIL-2	ns^3-151	ns	ns	19^3-152	ns	ns	ns	ns
	rIL-15	ns	22^3-153	ns	24^3-152	ns	ns	ns	ns
Case 4	Medium alone	+	+	−	+	+	−	+	+
	rIL-2	ns	ns	ns	ns	ns	ns	ns	ns
	rIL-15	ns	ns	ns	ns	29^3-153	ns	ns	ns
Case 17	Medium alone	−	+	−	+	+	−	+	+
	rIL-2	ns	ns	ns	ns	ns	ns	ns	ns
	rIL-15	ns	ns	ns	ns	ns	ns	ns	ns
Case 21	Medium alone	+	+	−	+	−	−	+	−
	rIL-2	ns	ns	ns	ns	ns	ns	ns	ns
	rIL-15	ns	ns	ns	ns	ns	ns	ns	ns

F3-150

Positivity was calculated by comparing the mean fluorescence intensity (MFI) of control and sample, as reported in the “Materials and methods” section.

F3-151

ns: not significant. The histogram obtained at resting conditions was compared with the histogram obtained after rIL-2 and rIL-15 stimulations. The statistical analysis was calculated using the Kolmogorov-Smirnov test and a D/s ratio >15 was accepted as significant.

F3-152

Indicates that the expression of antigen was up-modulated.

F3-153

Indicates that the expression of antigen was down-modulated.

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