Table 3. Hepatitis B–related hepatic... | American Society of Hematology

Table 3.

Hepatitis B–related hepatic events after allogeneic HCT group 1 and 2 patients

Patient no.	Recipients				Donors				HBV-related hepatitis		Recipients' last follow-up HBV serology
Patient no.	HBsAg/HBeAg/ Anti-HBe/ Anti-HBs	HBV DNA bDNA/PCR	A1896	T1762 and A1764	HBsAg/HBeAg/ HBeAb	HBV DNA bDNA/PCR	A1896	T1762 and A1764	Acute/ Chronic	Severity	HBsAg/HBeAg/ AntiHBe/ Anti-HBs
Group 1
	HBsAg-positive recipients
1	+/+/−/ND	+/+			+/+/−	−/+			Acute	Anicteric	+/+/−/ND
2	+/+/−/ND	+/+			+/−/+	−/+					+/−/−/ND
3	+/−/+/ND	+/+			+/−/+						+/−/+/ND
4	+/−/+/ND	−/+	−	+	+/−/+						+/−/+/ND
5	+/−/+/ND	−/+	+	+	+/−/+	−/+	−	+	Chronic	Anicteric	+/−/+/ND
6	+/−/+/ND	+/+	+	+	+/−/+	+/+	+	−	Chronic	HF^3-151	+/−/+/ND
7	+/−/+/ND	−/+			+/+/−	−/+			Chronic	HF^3-151	+/−/+/ND
8	+/−/+/ND	−/+	−	+	+/−/+						+/+/+/ND
9	+/−/+/ND	−/+	+	−	+/+/−	−/+					+/+/+/ND
	HBsAg negative recipients
10	−/ND/ND/+					−/+					−/ND/ND/+
11	−/ND/ND/+				+/+/−	+/+					−/ND/ND/+^3-150
12	−/ND/ND/+				+/−/+						−/ND/ND/+
13	−/ND/ND/+				+/−/+	+/+	+	−	Chronic	HF^3-151	+/+/ND/ND
14	−/ND/ND/+				+/+/−	+/+			Chronic	HF^3-151	+/+/ND/ND
15	−/ND/ND/−				+/−/+	+/+	+	+	Acute	HF	−/ND/ND/−^3-150
16	−/ND/ND/+				+/−/+	+/+	+	+	Acute	HF	+/+/ND/ND
17	−/ND/ND/−				+/−/+						−/ND/ND/−
18	−/ND/ND/−				+/−/+						−/ND/ND/−
Group 2
	HBsAg positive recipients
19	+/+/−/ND	+/+	−	−		−/+	+	−	Acute	Anicteric	+/+/−/ND
20	+/+/−/ND	+/+	−	−	−/+						+/−/−/ND
21	+/+/−/ND	+/+	−	−					Acute	Anicteric	+/+/−/ND
22	+/+/−/ND	+/+	−	+							+/+/−/ND
23	+/+/−/ND	+/+	−	−	+/−						+/+/−/ND
24	+/−/+/ND	−/+	+	−	+/+	−/+					−/−/ND/+
25	+/−/+/ND	−/−			+/+						−/−/ND/+
26	+/−/+/ND	−/+	+	+	+/+						−/−/ND/+
27	+/−/+/ND	−/−			+/+						+/−/+/ND
	HBsAg negative recipients
28	−/ND/ND/+	−/−									−/ND/ND/+
29	−/ND/ND/+	−/−									−/ND/ND/+
30	−/ND/ND/+	−/−			+/−						−/ND/ND/+
31	−/ND/ND/+	−/−			+/+						−/ND/ND/+
32	−/ND/ND/−	−/−									−/ND/ND/−
33	−/ND/ND/−	−/−			+/−						−/−/ND/+
34	−/ND/ND/−	−/−									−/ND/ND/−
35	−/ND/ND/−	−/−			+/−						−/−/ND/+
36	−/ND/ND/−	−/−									−/ND/ND/−

Patient no.	Recipients				Donors				HBV-related hepatitis		Recipients' last follow-up HBV serology
Patient no.	HBsAg/HBeAg/ Anti-HBe/ Anti-HBs	HBV DNA bDNA/PCR	A1896	T1762 and A1764	HBsAg/HBeAg/ HBeAb	HBV DNA bDNA/PCR	A1896	T1762 and A1764	Acute/ Chronic	Severity	HBsAg/HBeAg/ AntiHBe/ Anti-HBs
Group 1
	HBsAg-positive recipients
1	+/+/−/ND	+/+			+/+/−	−/+			Acute	Anicteric	+/+/−/ND
2	+/+/−/ND	+/+			+/−/+	−/+					+/−/−/ND
3	+/−/+/ND	+/+			+/−/+						+/−/+/ND
4	+/−/+/ND	−/+	−	+	+/−/+						+/−/+/ND
5	+/−/+/ND	−/+	+	+	+/−/+	−/+	−	+	Chronic	Anicteric	+/−/+/ND
6	+/−/+/ND	+/+	+	+	+/−/+	+/+	+	−	Chronic	HF^3-151	+/−/+/ND
7	+/−/+/ND	−/+			+/+/−	−/+			Chronic	HF^3-151	+/−/+/ND
8	+/−/+/ND	−/+	−	+	+/−/+						+/+/+/ND
9	+/−/+/ND	−/+	+	−	+/+/−	−/+					+/+/+/ND
	HBsAg negative recipients
10	−/ND/ND/+					−/+					−/ND/ND/+
11	−/ND/ND/+				+/+/−	+/+					−/ND/ND/+^3-150
12	−/ND/ND/+				+/−/+						−/ND/ND/+
13	−/ND/ND/+				+/−/+	+/+	+	−	Chronic	HF^3-151	+/+/ND/ND
14	−/ND/ND/+				+/+/−	+/+			Chronic	HF^3-151	+/+/ND/ND
15	−/ND/ND/−				+/−/+	+/+	+	+	Acute	HF	−/ND/ND/−^3-150
16	−/ND/ND/+				+/−/+	+/+	+	+	Acute	HF	+/+/ND/ND
17	−/ND/ND/−				+/−/+						−/ND/ND/−
18	−/ND/ND/−				+/−/+						−/ND/ND/−
Group 2
	HBsAg positive recipients
19	+/+/−/ND	+/+	−	−		−/+	+	−	Acute	Anicteric	+/+/−/ND
20	+/+/−/ND	+/+	−	−	−/+						+/−/−/ND
21	+/+/−/ND	+/+	−	−					Acute	Anicteric	+/+/−/ND
22	+/+/−/ND	+/+	−	+							+/+/−/ND
23	+/+/−/ND	+/+	−	−	+/−						+/+/−/ND
24	+/−/+/ND	−/+	+	−	+/+	−/+					−/−/ND/+
25	+/−/+/ND	−/−			+/+						−/−/ND/+
26	+/−/+/ND	−/+	+	+	+/+						−/−/ND/+
27	+/−/+/ND	−/−			+/+						+/−/+/ND
	HBsAg negative recipients
28	−/ND/ND/+	−/−									−/ND/ND/+
29	−/ND/ND/+	−/−									−/ND/ND/+
30	−/ND/ND/+	−/−			+/−						−/ND/ND/+
31	−/ND/ND/+	−/−			+/+						−/ND/ND/+
32	−/ND/ND/−	−/−									−/ND/ND/−
33	−/ND/ND/−	−/−			+/−						−/−/ND/+
34	−/ND/ND/−	−/−									−/ND/ND/−
35	−/ND/ND/−	−/−			+/−						−/−/ND/+
36	−/ND/ND/−	−/−									−/ND/ND/−

ND indicates not done. See the footnote to Table 1 for explanations of other abbreviations used.

F3-150

Transient HBsAg+ and HBeAg+.

F3-151

Died of HBV-related hepatic failure.

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