Table 3.

Associations between characteristics and death among 2950 males with hemophilia in six US states, 1993-1995

Characteristic Relative risk 95% CI P
Age (10-year increase)  1.6  1.4-1.7  <.001  
Race (white vs all other)  1.1  0.8-1.6  .56  
State of residence (vs New York)  
 Colorado  0.4  0.2-0.7  <.001 
 Georgia  0.8  0.6-1.2  .33  
 Louisiana  1.4 0.9-2.3  .13  
 Massachusetts  0.7  0.5-1.1  .11 
 Oklahoma  0.8  0.5-1.4  .52  
Hemophilia type (B vs A) 0.8  0.5-1.2  .35  
Disease severity (vs mild) 
 Moderate  0.7  0.5-1.1  .17  
 Severe  1.0 0.7-1.5  .89  
Insurance type (vs private/HMO) 
 Medicare/Medicaid  1.4  1.1-1.9  .01  
 Other/None 0.9  0.3-2.1  .75  
Inhibitor present  1.6  0.8-3.0 .18  
Liver disease  2.4  1.5-3.9  <.001 
HIV-infected without AIDS  4.7  3.0-7.2  <.001  
AIDS 33.5  22.7-49.5  <.001  
Hemophilia care source (HTC vs non-HTC)  0.6  0.5-0.8  .002 
Characteristic Relative risk 95% CI P
Age (10-year increase)  1.6  1.4-1.7  <.001  
Race (white vs all other)  1.1  0.8-1.6  .56  
State of residence (vs New York)  
 Colorado  0.4  0.2-0.7  <.001 
 Georgia  0.8  0.6-1.2  .33  
 Louisiana  1.4 0.9-2.3  .13  
 Massachusetts  0.7  0.5-1.1  .11 
 Oklahoma  0.8  0.5-1.4  .52  
Hemophilia type (B vs A) 0.8  0.5-1.2  .35  
Disease severity (vs mild) 
 Moderate  0.7  0.5-1.1  .17  
 Severe  1.0 0.7-1.5  .89  
Insurance type (vs private/HMO) 
 Medicare/Medicaid  1.4  1.1-1.9  .01  
 Other/None 0.9  0.3-2.1  .75  
Inhibitor present  1.6  0.8-3.0 .18  
Liver disease  2.4  1.5-3.9  <.001 
HIV-infected without AIDS  4.7  3.0-7.2  <.001  
AIDS 33.5  22.7-49.5  <.001  
Hemophilia care source (HTC vs non-HTC)  0.6  0.5-0.8  .002 

All characteristics were included in a multivariate analysis, using proportional hazards regression. Each relative risk has been adjusted for the effects of all other characteristics in the model. CI indicates confidence interval; HMO, health maintenance organization; HTC, hemophilia treatment center.

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