Comparison of bone marrow histopathology between polycythemia vera and secondary erythrocytosis
| . | Normal controls . | Polycythemia vera . | Secondary erythrocytosis . |
|---|---|---|---|
| No. of patients | 10 | 22 | 7 |
| Bone marrow iron stores | |||
| Increased | 0 | 1 | 0 |
| Normal | 1 | 2 | 5 |
| Absent | 0 | 15 | 2 |
| Not done/inadequate | 9 | 4 | 0 |
| Bone marrow cellularity | |||
| Normocellular | 10 | 2 | 4 |
| Mildly hypercellular | 0 | 8 | 2 |
| Markedly hypercellular | 0 | 12 | 1 |
| Megakaryocyte number | |||
| Normal | 10 | 4 | 5 |
| Mildly increased | 0 | 9 | 2 |
| Markedly increased | 0 | 9 | 0 |
| Megakaryocyte clusters | |||
| None | 10 | 5 | 6 |
| Few | 0 | 9 | 1 |
| Many | 0 | 8 | 0 |
| Giant megakaryocytes* | |||
| <10% | 10 | 5 | 7 |
| 10%-25% | 0 | 16 | 0 |
| >25% | 0 | 1 | 0 |
| . | Normal controls . | Polycythemia vera . | Secondary erythrocytosis . |
|---|---|---|---|
| No. of patients | 10 | 22 | 7 |
| Bone marrow iron stores | |||
| Increased | 0 | 1 | 0 |
| Normal | 1 | 2 | 5 |
| Absent | 0 | 15 | 2 |
| Not done/inadequate | 9 | 4 | 0 |
| Bone marrow cellularity | |||
| Normocellular | 10 | 2 | 4 |
| Mildly hypercellular | 0 | 8 | 2 |
| Markedly hypercellular | 0 | 12 | 1 |
| Megakaryocyte number | |||
| Normal | 10 | 4 | 5 |
| Mildly increased | 0 | 9 | 2 |
| Markedly increased | 0 | 9 | 0 |
| Megakaryocyte clusters | |||
| None | 10 | 5 | 6 |
| Few | 0 | 9 | 1 |
| Many | 0 | 8 | 0 |
| Giant megakaryocytes* | |||
| <10% | 10 | 5 | 7 |
| 10%-25% | 0 | 16 | 0 |
| >25% | 0 | 1 | 0 |
Diameter exceeding 30 μm on bone marrow section.