Initial characteristics of the 232 patients
| Characteristics . | No.patients . | (%) . | No. patients younger than 65* . | No. patients 65 or older* . |
|---|---|---|---|---|
| Total number of patients | 232 | 74 | 158 | |
| Sex | ||||
| Female | 67 | 29 | 21 (28) | 46 (29) |
| Male | 165 | 71 | 53 (72) | 112 (71) |
| Hepatomegaly | ||||
| Present | 49 | 21 | 17 (23) | 32 (20) |
| Absent | 183 | 79 | 57 (77) | 126 (80) |
| Splenomegaly† | ||||
| Present | 51 | 22 | 16 (22) | 35 (22) |
| Absent | 179 | 78 | 58 (78) | 121 (78) |
| Serum albumin (g/L)† | ||||
| Lower than 40 | 135 | 69 | 38 (60) | 97 (74) |
| At least 40 | 59 | 31 | 25 (40) | 34 (26) |
| Monoclonal IgM (g/L) | ||||
| Lower than 25 | 92 | 40 | 29 (39) | 63 (40) |
| At least 25 | 140 | 60 | 45 (61) | 95 (60) |
| Hemoglobin (g/dL)† | ||||
| Lower than 12 | 145 | 67 | 40 (57) | 105 (71) |
| At least 12 | 73 | 33 | 30 (43) | 43 (29) |
| Leukocytes (109/L)† | ||||
| Fewer than 4 | 16 | 8 | 5 (7) | 11 (7) |
| 4-10 | 176 | 77 | 56 (78) | 120 (79) |
| At least 10 | 32 | 15 | 11 (15) | 21 (14) |
| PMN count (109/L)† | ||||
| Fewer than 1.5 | 17 | 8 | 5 (7) | 12 (8) |
| 1.5 to 10 | 193 | 89 | 64 (89) | 129 (90) |
| More than 10 | 6 | 3 | 3 (4) | 3 (2) |
| Platelets (109/L)† | ||||
| Fewer than 150 | 46 | 20 | 11 (18) | 35 (25) |
| At least 150 | 167 | 80 | 61 (82) | 106 (75) |
| No. cytopenia† | ||||
| 0 | 57 | 28 | 28 (42) | 29 (21) |
| 1 | 105 | 52 | 30 (45) | 75 (55) |
| 2 | 33 | 16 | 6 (9) | 28 (20) |
| 3 | 8 | 4 | 3 (4) | 5 (4) |
| Characteristics . | No.patients . | (%) . | No. patients younger than 65* . | No. patients 65 or older* . |
|---|---|---|---|---|
| Total number of patients | 232 | 74 | 158 | |
| Sex | ||||
| Female | 67 | 29 | 21 (28) | 46 (29) |
| Male | 165 | 71 | 53 (72) | 112 (71) |
| Hepatomegaly | ||||
| Present | 49 | 21 | 17 (23) | 32 (20) |
| Absent | 183 | 79 | 57 (77) | 126 (80) |
| Splenomegaly† | ||||
| Present | 51 | 22 | 16 (22) | 35 (22) |
| Absent | 179 | 78 | 58 (78) | 121 (78) |
| Serum albumin (g/L)† | ||||
| Lower than 40 | 135 | 69 | 38 (60) | 97 (74) |
| At least 40 | 59 | 31 | 25 (40) | 34 (26) |
| Monoclonal IgM (g/L) | ||||
| Lower than 25 | 92 | 40 | 29 (39) | 63 (40) |
| At least 25 | 140 | 60 | 45 (61) | 95 (60) |
| Hemoglobin (g/dL)† | ||||
| Lower than 12 | 145 | 67 | 40 (57) | 105 (71) |
| At least 12 | 73 | 33 | 30 (43) | 43 (29) |
| Leukocytes (109/L)† | ||||
| Fewer than 4 | 16 | 8 | 5 (7) | 11 (7) |
| 4-10 | 176 | 77 | 56 (78) | 120 (79) |
| At least 10 | 32 | 15 | 11 (15) | 21 (14) |
| PMN count (109/L)† | ||||
| Fewer than 1.5 | 17 | 8 | 5 (7) | 12 (8) |
| 1.5 to 10 | 193 | 89 | 64 (89) | 129 (90) |
| More than 10 | 6 | 3 | 3 (4) | 3 (2) |
| Platelets (109/L)† | ||||
| Fewer than 150 | 46 | 20 | 11 (18) | 35 (25) |
| At least 150 | 167 | 80 | 61 (82) | 106 (75) |
| No. cytopenia† | ||||
| 0 | 57 | 28 | 28 (42) | 29 (21) |
| 1 | 105 | 52 | 30 (45) | 75 (55) |
| 2 | 33 | 16 | 6 (9) | 28 (20) |
| 3 | 8 | 4 | 3 (4) | 5 (4) |