A summary of experiments in which the indicated recipient mice were injected intravenously with FITC-labeled spleen cells or purified CD4+ cells from the indicated donor mice
| Donor cells . | Recipient . | % donor cells . | No. of mice . | |
|---|---|---|---|---|
| Spleen . | Lymph node . | |||
| DBA/2 CD4+ | C57BL/6 | 0.02 ± 0.02 | 0.04 ± 0.05 | 4 |
| C57BL/6 CD4+ | DBA/2 | 0.03 ± 0.03 | 0.08 ± 0.05 | 3 |
| C57BL/6 CD4+ | C57BL/6 | 1.35 ± 0.26 | 2.63 ± 0.35 | 2 |
| C57BL/6 | C57BL/6 | 1.49 ± 0.25 | 2.28 ± 0.13 | 3 |
| Donor cells . | Recipient . | % donor cells . | No. of mice . | |
|---|---|---|---|---|
| Spleen . | Lymph node . | |||
| DBA/2 CD4+ | C57BL/6 | 0.02 ± 0.02 | 0.04 ± 0.05 | 4 |
| C57BL/6 CD4+ | DBA/2 | 0.03 ± 0.03 | 0.08 ± 0.05 | 3 |
| C57BL/6 CD4+ | C57BL/6 | 1.35 ± 0.26 | 2.63 ± 0.35 | 2 |
| C57BL/6 | C57BL/6 | 1.49 ± 0.25 | 2.28 ± 0.13 | 3 |
The purified CD4+ cells contained 84% to 88% CD4+ cells and 13 to 25 × 106 cells were injected per recipient. Elimination of allogeneic donor CD4+ cells was significantly greater (P < .05) than elimination of syngeneic donor cells.