Genotypes of pups recovered using GATA-1 or mutated GATA-1 transgenes
| Line no. . | Transgene− . | Transgene+ . | ||||
|---|---|---|---|---|---|---|
| WT . | +/− female . | −/Y male . | WT . | +/− female . | −/Y male* . | |
| GATA-1 transgene | ||||||
| 782 | 23 | 5 | 0 | 4 | 1 | 3 |
| 801 | 11 | 1 | 0 | 13 | 3 | 5 |
| 831 | 11 | 3 | 0 | 4 | 5 | 3 |
| Total | 45 (47%) | 9 (9.5%) | 0 (0%) | 21 (22%) | 9 (9.5%) | 11 (12%) |
| Mutated GATA-1 transgene | ||||||
| 312 | 18 | 5 | 0 | 17 | 2 | 0 |
| 315 | 54 | 21 | 0 | 17 | 16 | 0 |
| Total | 72 (48%) | 26 (17%) | 0 (0%) | 34 (23%) | 18 (12%) | 0 (0%) |
| Line no. . | Transgene− . | Transgene+ . | ||||
|---|---|---|---|---|---|---|
| WT . | +/− female . | −/Y male . | WT . | +/− female . | −/Y male* . | |
| GATA-1 transgene | ||||||
| 782 | 23 | 5 | 0 | 4 | 1 | 3 |
| 801 | 11 | 1 | 0 | 13 | 3 | 5 |
| 831 | 11 | 3 | 0 | 4 | 5 | 3 |
| Total | 45 (47%) | 9 (9.5%) | 0 (0%) | 21 (22%) | 9 (9.5%) | 11 (12%) |
| Mutated GATA-1 transgene | ||||||
| 312 | 18 | 5 | 0 | 17 | 2 | 0 |
| 315 | 54 | 21 | 0 | 17 | 16 | 0 |
| Total | 72 (48%) | 26 (17%) | 0 (0%) | 34 (23%) | 18 (12%) | 0 (0%) |
Genotyping was performed on newborns.
G1R genotype.