Table 4. Peripheral blood indices from... | American Society of Hematology

Table 4.

Peripheral blood indices from rescued and transgenic mice with each transgene

Mouse strain	n	White blood cell count (×10²/μL)	Red blood cell count (×10⁴/μL)	Hemoglobin (g/dL)	Hematocrit (%)	Mean corpuscular volume (fL)	Mean corpuscular hemoglobin (pg)	Mean corpuscular hemoglobin concentration (g/dL)	Platelet count (×10⁴/μL)
WT	27	92.3 ± 54.6	872.5 ± 68.7^4-150	13.4 ± 1.1^4-150,^4-151	42.8 ± 3.1^4-150,^4-151	49.1 ± 2.7	15.3 ± 1.0	31.2 ± 0.8^4-150,^4-151	75.2 ± 19.2^4-150,^4-151
G1R	6	93.0 ± 40.7	765.7 ± 79.7	12.0 ± 1.0	39.2 ± 3.1	51.3 ± 2.1	15.6 ± 0.9	30.5 ± 1.4	54.4 ± 17.7
G2R	18	88.3 ± 27.6	759.2 ± 133.4	10.8 ± 1.5^4-150	36.1 ± 4.8^4-150	48.1 ± 3.8	14.3 ± 1.3	29.8 ± 0.9^4-150	35.2 ± 12.6^4-150
G3R	20	116.2 ± 78.3	615.5 ± 244.7^4-150	8.6 ± 2.9^4-151	29.1 ± 10.0^4-151	49.3 ± 6.1	14.6 ± 1.9	29.5 ± 1.0^4-151	21.1 ± 7.3^4-151
G1 Tg	—	ND	ND	ND	ND	ND	ND	ND	ND
G2 Tg	13	101.2 ± 56.5	843.8 ± 160.7	12.0 ± 2.1	39.2 ± 7.0	47.1 ± 3.8	14.4 ± 1.3	30.7 ± 0.8	54.9 ± 23.3
G3 Tg	16	86.9 ± 20.1	888.1 ± 132.2	12.7 ± 1.6	40.9 ± 5.6	46.3 ± 3.4	14.3 ± 1.2	31.0 ± 0.7	68.5 ± 9.6

Mouse strain	n	White blood cell count (×10²/μL)	Red blood cell count (×10⁴/μL)	Hemoglobin (g/dL)	Hematocrit (%)	Mean corpuscular volume (fL)	Mean corpuscular hemoglobin (pg)	Mean corpuscular hemoglobin concentration (g/dL)	Platelet count (×10⁴/μL)
WT	27	92.3 ± 54.6	872.5 ± 68.7^4-150	13.4 ± 1.1^4-150,^4-151	42.8 ± 3.1^4-150,^4-151	49.1 ± 2.7	15.3 ± 1.0	31.2 ± 0.8^4-150,^4-151	75.2 ± 19.2^4-150,^4-151
G1R	6	93.0 ± 40.7	765.7 ± 79.7	12.0 ± 1.0	39.2 ± 3.1	51.3 ± 2.1	15.6 ± 0.9	30.5 ± 1.4	54.4 ± 17.7
G2R	18	88.3 ± 27.6	759.2 ± 133.4	10.8 ± 1.5^4-150	36.1 ± 4.8^4-150	48.1 ± 3.8	14.3 ± 1.3	29.8 ± 0.9^4-150	35.2 ± 12.6^4-150
G3R	20	116.2 ± 78.3	615.5 ± 244.7^4-150	8.6 ± 2.9^4-151	29.1 ± 10.0^4-151	49.3 ± 6.1	14.6 ± 1.9	29.5 ± 1.0^4-151	21.1 ± 7.3^4-151
G1 Tg	—	ND	ND	ND	ND	ND	ND	ND	ND
G2 Tg	13	101.2 ± 56.5	843.8 ± 160.7	12.0 ± 2.1	39.2 ± 7.0	47.1 ± 3.8	14.4 ± 1.3	30.7 ± 0.8	54.9 ± 23.3
G3 Tg	16	86.9 ± 20.1	888.1 ± 132.2	12.7 ± 1.6	40.9 ± 5.6	46.3 ± 3.4	14.3 ± 1.2	31.0 ± 0.7	68.5 ± 9.6

“n” indicates number of mice examined. Data was corrected from 2- to 23-month-old mice. ND indicates not determined.

P < .001.

P < .001.