Peritoneal macrophage and lymphocyte populations in wt and Lsp1−/− mice
| Cell population . | Percentage of total cells . | |
|---|---|---|
| wt . | Lsp1−/− . | |
| Macrophages | ||
| Mac-1hiCD5− | 10.9 ± 1.4 (8) | 31.0 ± 3.4 (9)* |
| Mac-1hiCD5+ | 3.7 ± 0.5 (8) | 3.9 ± 0.8 (9) |
| F4/80+Mac-1hi | 16.2 ± 2.9 (5) | 29.9 ± 2.6 (5)† |
| Lymphocytes | 67.6 ± 2.7 (8) | 47.4 ± 2.9 (9)* |
| Cell population . | Percentage of total cells . | |
|---|---|---|
| wt . | Lsp1−/− . | |
| Macrophages | ||
| Mac-1hiCD5− | 10.9 ± 1.4 (8) | 31.0 ± 3.4 (9)* |
| Mac-1hiCD5+ | 3.7 ± 0.5 (8) | 3.9 ± 0.8 (9) |
| F4/80+Mac-1hi | 16.2 ± 2.9 (5) | 29.9 ± 2.6 (5)† |
| Lymphocytes | 67.6 ± 2.7 (8) | 47.4 ± 2.9 (9)* |
Values represent mean percentage ± 1 SEM. Numbers in parentheses correspond to the number of mice.
P ≤ .0003.
P = .008.
Lymphocytes are analyzed from FSC/SSC profiles as shown in Figure 3. The CD5− macrophage numbers based on the total peritoneal cell numbers (see “Results”) are 0.59 × 106± 0.07 × 106 versus 1.75 × 106 ± 0.19 × 106 in wt versusLsp1−/− mice, respectively.