Table 6. Relationship between PEG-Asp... | American Society of Hematology

Table 6.

Relationship between PEG-Asp antibodies and Escherichia coli asparaginase antibodies with asparaginase levels

N	Asparaginase level^6-150	Asparaginase antibody
N	Asparaginase level^6-150	Asp Ab (mean % ± SD)^6-151	PEG-Asp Ab (mean % ± SD)^6-152
60	≥ 0.03 U/mL	5.4 ± 9.0	4.3 ± 14.1
16	< 0.03 U/mL	129 ± 196	48 ± 45

N	Asparaginase level^6-150	Asparaginase antibody
N	Asparaginase level^6-150	Asp Ab (mean % ± SD)^6-151	PEG-Asp Ab (mean % ± SD)^6-152
60	≥ 0.03 U/mL	5.4 ± 9.0	4.3 ± 14.1
16	< 0.03 U/mL	129 ± 196	48 ± 45

Asp Ab = Escherichia coli asparaginase antibodies.

PEG-Asp Ab = polyethylene glycol asparaginase antibodies.

Asp level ≥ 0.03 U/mL corresponds to asparagine depletion.

P = .024.

P = .0013.