Neutrophil NADPH oxidase activity after transduction of normal and patient bone marrow cells
| Agonist . | Normal BM MIEG3 (%)* . | Patient BM MIEG3 (%) . | Patient BM MIEG3FR2 (%) . |
|---|---|---|---|
| PMA | 91 | 62 | 52 |
| fMLP | 55 | 1 | 4 |
| No stimulant | 20 | 0 | 1 |
| Agonist . | Normal BM MIEG3 (%)* . | Patient BM MIEG3 (%) . | Patient BM MIEG3FR2 (%) . |
|---|---|---|---|
| PMA | 91 | 62 | 52 |
| fMLP | 55 | 1 | 4 |
| No stimulant | 20 | 0 | 1 |
NADPH oxidase activity was monitored in individual neutrophils using the NBT test, as described in “Materials and methods.”
Percentage NBT positive.