Megakaryocyte number, size, and ploidy level are affected by IFN-α
| . | % cell no. . | Cell size (μm) . | Geometric mean ploidy . |
|---|---|---|---|
| 3 ng/mL TPO | 100 | 44.2 | 17.0 N |
| 3 ng/mL TPO + 500 U/mL IFN-α | 81 | 39.9 | 14.6 N |
| . | % cell no. . | Cell size (μm) . | Geometric mean ploidy . |
|---|---|---|---|
| 3 ng/mL TPO | 100 | 44.2 | 17.0 N |
| 3 ng/mL TPO + 500 U/mL IFN-α | 81 | 39.9 | 14.6 N |
Lin−/CD41+ cells were cultured in TPO for 3 days, and the cells were analyzed by propidium iodide staining for DNA content and by a calibrated microscope for cell size. Data represent the mean ± SEM of three independent experiments.P < .05 for all comparisons.