Immunoglobulin isotype protein expression
Case no. . | Flow cytometry . | Immunohistochemistry, % of positive tumor cells . | ||||
---|---|---|---|---|---|---|
IgM . | IgD . | IgG . | IgA . | Light chain . | ||
5049 | sIgM/D/κ | 100 | − | 30 | − | 100 κ |
5126 | SigM/λ | 100 | − | 5-10 | single cells4-150 | 100 λ |
5184 | na | 100 | 30 | − | − | 100 κ |
5334 | sIgM/D/κ | na4-151 | na4-151 | na4-151 | na4-151 | na4-151 |
Case no. . | Flow cytometry . | Immunohistochemistry, % of positive tumor cells . | ||||
---|---|---|---|---|---|---|
IgM . | IgD . | IgG . | IgA . | Light chain . | ||
5049 | sIgM/D/κ | 100 | − | 30 | − | 100 κ |
5126 | SigM/λ | 100 | − | 5-10 | single cells4-150 | 100 λ |
5184 | na | 100 | 30 | − | − | 100 κ |
5334 | sIgM/D/κ | na4-151 | na4-151 | na4-151 | na4-151 | na4-151 |
na indicates not available; − indicates negative.
Indicates that single IgA-bearing cells were detected. Because there were no positive confluent groups of cells, however, it was not possible to definitely attribute these cells to the tumor cell population on morphological grounds.
The morphology in case 5334 was poorly maintained in the paraffin-embedded material.