Table 4.

Immunoglobulin isotype protein expression

Case no.Flow cytometryImmunohistochemistry, % of positive tumor cells
IgMIgDIgGIgALight chain
5049 sIgM/D/κ 100 − 30 − 100 κ  
5126 SigM/λ 100 − 5-10 single cells4-150 100 λ  
5184 na 100 30 − − 100 κ 
5334 sIgM/D/κ na4-151 na4-151 na4-151 na4-151 na4-151 
Case no.Flow cytometryImmunohistochemistry, % of positive tumor cells
IgMIgDIgGIgALight chain
5049 sIgM/D/κ 100 − 30 − 100 κ  
5126 SigM/λ 100 − 5-10 single cells4-150 100 λ  
5184 na 100 30 − − 100 κ 
5334 sIgM/D/κ na4-151 na4-151 na4-151 na4-151 na4-151 

na indicates not available; − indicates negative.

F4-150

Indicates that single IgA-bearing cells were detected. Because there were no positive confluent groups of cells, however, it was not possible to definitely attribute these cells to the tumor cell population on morphological grounds.

F4-151

The morphology in case 5334 was poorly maintained in the paraffin-embedded material.

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