Table 1.

ICE chemotherapy

Day 1Day 2Day 3Days 5-12
Ifosfamide    
Carboplatin    
Etoposide  
G-CSF    
Day 1Day 2Day 3Days 5-12
Ifosfamide    
Carboplatin    
Etoposide  
G-CSF    

Ifosfamide: 5 g/m2 mixed with an equal amount of mesna and administered over 24 hours. Carboplatin: dosed at an area under the curve of 5 (5× [creatinine clearance + 25]) and capped at 800 mg, administered as a bolus. Etoposide: 100 mg/m2, administered as a bolus. G-CSF: 5 μg/kg for the first two cycles, then 10 μg/kg beginning on day 5 of the third cycle and continuing through leukapheresis. Cycles were to be administered every 14 days, for a total of 3 cycles.

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