Comparison of monoclonal gammopathy of undetermined significance and asymptomatic myeloma
| Characteristic . | MGUS . | Asymptomatic myeloma . |
|---|---|---|
| Monoclonal protein | < 30 g/L | > 20 g/L in 85% |
| Marrow plasma cells | < 10% | > 10% |
| Uninvolved immunoglobulins | Preserved in 80% | Depressed in 90% |
| Urinary protein (Bence Jones) | None or < 50 mg/d | > 50 mg/d in 35% |
| Spine MRI results | Normal | Abnormal in 40% |
| Characteristic . | MGUS . | Asymptomatic myeloma . |
|---|---|---|
| Monoclonal protein | < 30 g/L | > 20 g/L in 85% |
| Marrow plasma cells | < 10% | > 10% |
| Uninvolved immunoglobulins | Preserved in 80% | Depressed in 90% |
| Urinary protein (Bence Jones) | None or < 50 mg/d | > 50 mg/d in 35% |
| Spine MRI results | Normal | Abnormal in 40% |
MGUS indicates monoclonal gammopathy of undetermined significance; MRI, magnetic resonance imaging.