Interaction of bacteria or bacterial products with plasmin(ogen)
| Bacterial species . | Gram reaction . | Interactions investigated . | Reference . |
|---|---|---|---|
| Borrelia burgdorferi | Gram-negative | Activation of bound plasminogen in the presence of host-derived plasminogen activators | 130, 132, 135 |
| Escherichia coli | Gram-negative | Binding of plasminogen to G fimbria and curli organelles followed by activation by tPA | 131, 179 |
| Fusobacterium nucleatum | Gram-negative | Activation of bound plasminogen by streptokinase, uPA, or Porphyromonas gingivalis culture supernatant | 180 |
| Helicobacter pylori | Gram-negative | Determination of binding constants and mapping of bacterial-binding site in plasminogen | 122, 181 |
| Mycoplasma fermentans | Gram-negative | Activation of bound plasminogen by tPA | 182 |
| Neisseria gonorrhoeae | Gram-negative | Determination of the number of bacterial binding sites for plasminogen, activation by tPA, and measurements of plasmin activity on the cell surface | 183 |
| Neisseria meningitidis | Gram-negative | Determination of the number of bacterial binding sites for plasminogen, activation by tPA, and measurements of plasmin activity on the cell surface | 183 |
| Pseudomonas aeruginosa | Gram-negative | Degradation of plasminogen and plasmin by an extracellular protease | 184, 185 |
| Salmonella enteritidis | Gram-negative | Binding of plasminogen to thin aggregative fimbriae followed by activation by tPA | 131 |
| Salmonella typhimurium | Gram-negative | Binding of plasminogen to type 1 fimbria | 179 |
| Staphylococcus aureus | Gram-positive | Determination of the number of bacterial-binding sites for plasminogen, activation by tPA, and measurements of plasmin activity on the cell surface | 186 |
| Streptococcus species; group A, C, and G | Gram-positive | Binding of plasminogen to M and M-like proteins, activation of bound plasminogen by streptokinase | 134, 187, 188 |
| Yersinia pestis | Gram-negative | Studies on the role of an outer membrane plasminogen activator in systemic infection | 128,129 |
| Bacterial species . | Gram reaction . | Interactions investigated . | Reference . |
|---|---|---|---|
| Borrelia burgdorferi | Gram-negative | Activation of bound plasminogen in the presence of host-derived plasminogen activators | 130, 132, 135 |
| Escherichia coli | Gram-negative | Binding of plasminogen to G fimbria and curli organelles followed by activation by tPA | 131, 179 |
| Fusobacterium nucleatum | Gram-negative | Activation of bound plasminogen by streptokinase, uPA, or Porphyromonas gingivalis culture supernatant | 180 |
| Helicobacter pylori | Gram-negative | Determination of binding constants and mapping of bacterial-binding site in plasminogen | 122, 181 |
| Mycoplasma fermentans | Gram-negative | Activation of bound plasminogen by tPA | 182 |
| Neisseria gonorrhoeae | Gram-negative | Determination of the number of bacterial binding sites for plasminogen, activation by tPA, and measurements of plasmin activity on the cell surface | 183 |
| Neisseria meningitidis | Gram-negative | Determination of the number of bacterial binding sites for plasminogen, activation by tPA, and measurements of plasmin activity on the cell surface | 183 |
| Pseudomonas aeruginosa | Gram-negative | Degradation of plasminogen and plasmin by an extracellular protease | 184, 185 |
| Salmonella enteritidis | Gram-negative | Binding of plasminogen to thin aggregative fimbriae followed by activation by tPA | 131 |
| Salmonella typhimurium | Gram-negative | Binding of plasminogen to type 1 fimbria | 179 |
| Staphylococcus aureus | Gram-positive | Determination of the number of bacterial-binding sites for plasminogen, activation by tPA, and measurements of plasmin activity on the cell surface | 186 |
| Streptococcus species; group A, C, and G | Gram-positive | Binding of plasminogen to M and M-like proteins, activation of bound plasminogen by streptokinase | 134, 187, 188 |
| Yersinia pestis | Gram-negative | Studies on the role of an outer membrane plasminogen activator in systemic infection | 128,129 |
TPA indicates tissue plasminogen activator; uPA, urokinase-type plasminogen activator.