Clinical features of 3 DLBCL cases with BCL6 translocation affecting the 3q26-27 locus
| Case no. . | Age (y)/ sex . | Stage/PS . | Involved organs at presentation . | LDH (IU) . | Treatment . | Outcome . | Survival (d) . |
|---|---|---|---|---|---|---|---|
| 90 | 70/M | III/1 | Lymph nodes | 735 | CHOP, radiation | CR-R-PD | 630 |
| 880 | 59/M | IV/1 | Lymph nodes, spleen, bone marrow, liver | 1950 | LSG4* | PD | 30 |
| 910 | 35/F | IVE/3 | Lymph nodes, breasts, ovary, uterus | 737 | Mastectomy, CHOP, high-dose chemotherapy | PR-R-PD | 501 |
| Case no. . | Age (y)/ sex . | Stage/PS . | Involved organs at presentation . | LDH (IU) . | Treatment . | Outcome . | Survival (d) . |
|---|---|---|---|---|---|---|---|
| 90 | 70/M | III/1 | Lymph nodes | 735 | CHOP, radiation | CR-R-PD | 630 |
| 880 | 59/M | IV/1 | Lymph nodes, spleen, bone marrow, liver | 1950 | LSG4* | PD | 30 |
| 910 | 35/F | IVE/3 | Lymph nodes, breasts, ovary, uterus | 737 | Mastectomy, CHOP, high-dose chemotherapy | PR-R-PD | 501 |
PS indicates performance status; LDH, lactic dehydrogenase; M, male; F, female. CHOP indicates cyclophosphamide, doxorubicin, vincristine, and prednisone. CR indicates complete remission; PR, partial remission; R, relapse; and PD, progressive disease. Details of the clinical features of case no. 910 were described previously.17
LSG4 is the multidrug regimen proposed by the Japan Lymphoma Study Group.