Table 3. Frequency of individuals with... | American Society of Hematology

Table 3.

Frequency of individuals with skewed TCR BV repertoire in PNH and control groups as determined by the three-criteria analysis^3-151

TCR family	Controls^3-150 (%)	PNH patients (%)	P value
BV1	19	27	NS
BV2	7	11	NS
BV3	17	32	NS
BV4	0	29	0.04
BV5	6	16	NS
BV6	13	15	NS
BV7	0	44	0.003
BV8	22	28	NS
BV9	17	42	NS
BV11	17	29	NS
BV12	8	46	NS
BV13	6	28	NS
BV14	6	24	NS
BV15	40	26	NS
BV16	13	37	NS
BV17	11	26	NS
BV18	12	29	NS
BV21	22	38	NS
BV22	7	29	NS
BV23	0	40	0.02
BV24	0	38	0.04

TCR family	Controls^3-150 (%)	PNH patients (%)	P value
BV1	19	27	NS
BV2	7	11	NS
BV3	17	32	NS
BV4	0	29	0.04
BV5	6	16	NS
BV6	13	15	NS
BV7	0	44	0.003
BV8	22	28	NS
BV9	17	42	NS
BV11	17	29	NS
BV12	8	46	NS
BV13	6	28	NS
BV14	6	24	NS
BV15	40	26	NS
BV16	13	37	NS
BV17	11	26	NS
BV18	12	29	NS
BV21	22	38	NS
BV22	7	29	NS
BV23	0	40	0.02
BV24	0	38	0.04

F3-151

R-square < 0.55 or any peak 40% above the fitted value at the median point or any peak double or half of that at the corresponding peak of the fitted curve.

F3-150

Healthy and transfused controls combined.

NS: not significant.

View Large

This Feature Is Available To Subscribers Only