Demographic and clinical characteristics of the first 204 patients who underwent transplantation with PCB grafts from unrelated donors with colony-forming cell counts from the New York Blood Center
| Characteristic . | Number (%) . |
|---|---|
| Male | 130 (64) |
| Female | 74 (36) |
| Age at transplantation (y) | |
| <2 | 57 (28) |
| 2-5 | 49 (24) |
| 6-11 | 46 (23) |
| 12-17 | 28 (14) |
| ≥18 | 24 (12) |
| Diagnosis | |
| Leukemia/lymphoma | 125 (61) |
| Acute lymphoblastic leukemia | 58 (46) |
| Acute myeloblastic leukemia | 46 (37) |
| Chronic myelogenous leukemia | 10 (8) |
| Juvenile chronic myelogenous leukemia | 7 (6) |
| Lymphoma | 4 (3) |
| Genetic disease | 62 (30) |
| Fanconi anemia | 19 (31) |
| Severe combined immunodeficiency | 9 (15) |
| Osteopetrosis | 4 (7) |
| Hurler syndrome | 3 (5) |
| Wiskott-Aldrich syndrome | 3 (5) |
| Adrenoleukodystrophy | 3 (5) |
| Blackfan-Diamond | 3 (5) |
| Other genetic | 18 (29) |
| Acquired diseases | 17 (8) |
| Myelodysplastic disease | 6 (35) |
| Severe aplastic anemia | 8 (47) |
| Other cancer | 3 (18) |
| Number of HLA-A, -B, -DR mismatches (including high-resolution DR*) | |
| 0 | 18 (9) |
| 1 | 89 (44) |
| ≥2 | 96 (47) |
| Location of transplantation center | |
| United States | 177 (87) |
| Outside United States | 27 (13) |
| Characteristic . | Number (%) . |
|---|---|
| Male | 130 (64) |
| Female | 74 (36) |
| Age at transplantation (y) | |
| <2 | 57 (28) |
| 2-5 | 49 (24) |
| 6-11 | 46 (23) |
| 12-17 | 28 (14) |
| ≥18 | 24 (12) |
| Diagnosis | |
| Leukemia/lymphoma | 125 (61) |
| Acute lymphoblastic leukemia | 58 (46) |
| Acute myeloblastic leukemia | 46 (37) |
| Chronic myelogenous leukemia | 10 (8) |
| Juvenile chronic myelogenous leukemia | 7 (6) |
| Lymphoma | 4 (3) |
| Genetic disease | 62 (30) |
| Fanconi anemia | 19 (31) |
| Severe combined immunodeficiency | 9 (15) |
| Osteopetrosis | 4 (7) |
| Hurler syndrome | 3 (5) |
| Wiskott-Aldrich syndrome | 3 (5) |
| Adrenoleukodystrophy | 3 (5) |
| Blackfan-Diamond | 3 (5) |
| Other genetic | 18 (29) |
| Acquired diseases | 17 (8) |
| Myelodysplastic disease | 6 (35) |
| Severe aplastic anemia | 8 (47) |
| Other cancer | 3 (18) |
| Number of HLA-A, -B, -DR mismatches (including high-resolution DR*) | |
| 0 | 18 (9) |
| 1 | 89 (44) |
| ≥2 | 96 (47) |
| Location of transplantation center | |
| United States | 177 (87) |
| Outside United States | 27 (13) |
HLA indicates human leukocyte antigen.
One patient was not typed for high-resolution DRB1.