Overall response (CR + PR) to 2-CdA + P vs Chl + P as a first-line treatment of patients with CLL according to Rai stage and age
| Characteristics . | 2-CdA + P . | Chl + P . | P3-150 . | ||
|---|---|---|---|---|---|
| No. patients . | OR (%) . | No. patients . | OR (%) . | ||
| All patients | 126 | 109 (87) | 103 | 58 (57) | |
| Rai stage at beginning of treatment | |||||
| 0 | 5 | 5 (100) | 5 | 3 (60) | .4 |
| I + II | 65 | 63 (97) | 61 | 37 (61) | <.0001 |
| III + IV | 56 | 41 (73) | 37 | 19 (51) | .03 |
| P | .0005 | .6 | |||
| Age (y) | |||||
| > 70 | 18 | 16 (89) | 14 | 7 (50) | .04 |
| 55-75 | 68 | 57 (84) | 57 | 33 (58) | .03 |
| < 55 | 40 | 36 (90) | 32 | 19 (60) | .006 |
| P | .6 | .8 | |||
| Characteristics . | 2-CdA + P . | Chl + P . | P3-150 . | ||
|---|---|---|---|---|---|
| No. patients . | OR (%) . | No. patients . | OR (%) . | ||
| All patients | 126 | 109 (87) | 103 | 58 (57) | |
| Rai stage at beginning of treatment | |||||
| 0 | 5 | 5 (100) | 5 | 3 (60) | .4 |
| I + II | 65 | 63 (97) | 61 | 37 (61) | <.0001 |
| III + IV | 56 | 41 (73) | 37 | 19 (51) | .03 |
| P | .0005 | .6 | |||
| Age (y) | |||||
| > 70 | 18 | 16 (89) | 14 | 7 (50) | .04 |
| 55-75 | 68 | 57 (84) | 57 | 33 (58) | .03 |
| < 55 | 40 | 36 (90) | 32 | 19 (60) | .006 |
| P | .6 | .8 | |||
P values were calculated to compare OR (overall responder) and NR (nonresponder) groups.