Table 5.

Response to second-line treatment

First line5-150No. NR or relapsed patients < 12 moSecond line5-150No. patients treated with second lineResponse (%)5-151
CRPRNR
2-CdA + P 34 Chl + P 26 7  (27) 19  (73)  
Chl + P 77 2-CdA + P 43 10 (23) 19  (44) 14  (33) 
First line5-150No. NR or relapsed patients < 12 moSecond line5-150No. patients treated with second lineResponse (%)5-151
CRPRNR
2-CdA + P 34 Chl + P 26 7  (27) 19  (73)  
Chl + P 77 2-CdA + P 43 10 (23) 19  (44) 14  (33) 
F5-150

Patients with no response (NR) or progression after 3 courses of first-line treatment or patients who had relapses earlier than 12 months after completing the treatment were switched to an alternative arm (second-line treatment).

F5-151

Comparison of CR + PR and NR groups: P = .03.

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