Frequency of identical T-cell clones in the skin and peripheral blood, according to histologic diagnosis in 363 patients assessed by polymerase chain reaction-γ-denaturing gradient gel electrophoresis
| Diagnosis (no. of patients) . | Mean age (range) . | Skin positive for clone, no. (%) of patients . | PB positive for identical clone, no. (%) of patients . |
|---|---|---|---|
| MF (88) | 60 (17-94) | 55 (62.5) | 11 (12.5) |
| SS (22) | 65 (45-88) | 17 (77) | 15 (68) |
| PTCL (28) | 52 (14-91) | 26 (93) | 7 (25) |
| LyP (14) | 40 (10-79) | 8 (57) | 0 |
| All CTCL (152) | 57 (14-94) | 106 (70) | 33 (22) |
| Benign dermatoses (72) | 55 (7-93) | 17 (24)* | 2 (3) |
| Non-CTCL MD (27) | 67 (38-91) | 7 (26) | 0 |
| Uncertain MF (27) | 64 (19-87) | 6 (22) | 1 (4) |
| Nonspecific (85) | 61 (13-91) | 21 (25) | 10 (12) |
| All non-CTCL (211) | 60 (7-91) | 51 (24) | 13 (6) |
| Diagnosis (no. of patients) . | Mean age (range) . | Skin positive for clone, no. (%) of patients . | PB positive for identical clone, no. (%) of patients . |
|---|---|---|---|
| MF (88) | 60 (17-94) | 55 (62.5) | 11 (12.5) |
| SS (22) | 65 (45-88) | 17 (77) | 15 (68) |
| PTCL (28) | 52 (14-91) | 26 (93) | 7 (25) |
| LyP (14) | 40 (10-79) | 8 (57) | 0 |
| All CTCL (152) | 57 (14-94) | 106 (70) | 33 (22) |
| Benign dermatoses (72) | 55 (7-93) | 17 (24)* | 2 (3) |
| Non-CTCL MD (27) | 67 (38-91) | 7 (26) | 0 |
| Uncertain MF (27) | 64 (19-87) | 6 (22) | 1 (4) |
| Nonspecific (85) | 61 (13-91) | 21 (25) | 10 (12) |
| All non-CTCL (211) | 60 (7-91) | 51 (24) | 13 (6) |
PB indicates peripheral blood; MF, mycosis fungoides; SS, Sézary syndrome; PTCL, pleomorphic T-cell lymphoma; LyP, lymphomatoid papulosis; CTCL, cutaneous T-cell lymphomas, and MD, malignant disease.
The histologic diagnoses were benign follicular mucinosis (3 patients), contact dermatitis (3), benign panniculitis (3), pityriasis lichenoides (2), cutaneous lymphoid hyperplasia (2), Jessner-Kanof infiltration (1), drug-induced dermatoses (1), folliculitis (1), and pemphigoides (1).