Test results for selected patients with lymphoproliferative disease of granular T lymphocytes presenting as aplastic anemia
| . | No. of patients . |
|---|---|
| Direct antiglobulin test (n = 5) | |
| Positive | 1 |
| Antinuclear antibody test (n = 6) | |
| Positive | 2 |
| Cytogenetic studies (n = 8) | |
| Normal | 4 |
| Loss of Y chromosome | 3 |
| Translocation (1;7) | 1 |
| Peripheral blood flow cytometry (n = 6)* | |
| Inverted CD4:CD8 ratio | 2 |
| Normal | 4 |
| Bone marrow immunohistochemistry (n = 8) | |
| Increase in CD3+ cells and CD8+ cells | 8 |
| Increase in CD57+ cells | 7 |
| . | No. of patients . |
|---|---|
| Direct antiglobulin test (n = 5) | |
| Positive | 1 |
| Antinuclear antibody test (n = 6) | |
| Positive | 2 |
| Cytogenetic studies (n = 8) | |
| Normal | 4 |
| Loss of Y chromosome | 3 |
| Translocation (1;7) | 1 |
| Peripheral blood flow cytometry (n = 6)* | |
| Inverted CD4:CD8 ratio | 2 |
| Normal | 4 |
| Bone marrow immunohistochemistry (n = 8) | |
| Increase in CD3+ cells and CD8+ cells | 8 |
| Increase in CD57+ cells | 7 |
Immunophenotypes studied include CD2, CD3, CD5, CD7, CD3/CD8, CD3/CD4.