Percentage of human hematopoietic cells detected in the bone marrow of NOD/SCID mice 5 to 11 weeks after transplantation with human PBCs or CBCs
| Marker . | Transplanted cell population . | ||
|---|---|---|---|
| PBC-CD34+ . | CBC-MNC . | CBC-CD34+ . | |
| CD45 | 15.5 (0.7-43.5) | 17 (4.5-40) | 58 (50-72) |
| CD2 | ND | 2.1 (1.0-4.6) | ND |
| CD7 | ND | 0.1 (0.0-0.3) | ND |
| CD10 | 3.2 (0.2-12.4) | 17.2 (5.0-38) | ND |
| CD13 | 8.2 (1.5-22.6) | 1.9 (1.3-2.7) | 5.3 (4.0-6.0) |
| CD14 | 4.9 (0.6-10.2) | 0 | ND |
| CD19 | 5.4 (1.2-19.0) | 14.7 (2.0-34.4) | ND |
| CD33 | 7.2 (2.6-18.1) | 2.4 (1.5-4.1) | 10.3 (6.0-18) |
| CD34 | 1.7 (0.5-3.3) | 2.3 (0.5-3.2) | 6.5 (3.0-12) |
| CD38 | 12.5 (2.1-27.5) | 16.7 (4.0-38) | 61 (50-65) |
| HLA-I | 27.0 (1.3-46.2) | 16.8 (3.7-37.7) | 63 (60-70) |
| Marker . | Transplanted cell population . | ||
|---|---|---|---|
| PBC-CD34+ . | CBC-MNC . | CBC-CD34+ . | |
| CD45 | 15.5 (0.7-43.5) | 17 (4.5-40) | 58 (50-72) |
| CD2 | ND | 2.1 (1.0-4.6) | ND |
| CD7 | ND | 0.1 (0.0-0.3) | ND |
| CD10 | 3.2 (0.2-12.4) | 17.2 (5.0-38) | ND |
| CD13 | 8.2 (1.5-22.6) | 1.9 (1.3-2.7) | 5.3 (4.0-6.0) |
| CD14 | 4.9 (0.6-10.2) | 0 | ND |
| CD19 | 5.4 (1.2-19.0) | 14.7 (2.0-34.4) | ND |
| CD33 | 7.2 (2.6-18.1) | 2.4 (1.5-4.1) | 10.3 (6.0-18) |
| CD34 | 1.7 (0.5-3.3) | 2.3 (0.5-3.2) | 6.5 (3.0-12) |
| CD38 | 12.5 (2.1-27.5) | 16.7 (4.0-38) | 61 (50-65) |
| HLA-I | 27.0 (1.3-46.2) | 16.8 (3.7-37.7) | 63 (60-70) |
Values are means with the highest and lowest values shown in parentheses.
Analysis was done by flow cytometry of bone marrow cell suspensions (n = 6-20) as described in “Patients, materials, and methods.”
ND indicates not determined; MNC, mononuclear cell fraction.