Human CRU frequencies in initial cord blood and fetal liver cell suspensions
Cells injected into mice . | No. cells injected per mouse . | Proportion of negative mice . | CRU frequency (per 106 cells) . |
---|---|---|---|
CB | 3 × 106 | 3 of 21 | 1.0 |
1 × 106 | 7 of 21 | (0.8-1.2)* | |
3 × 105 | 13 of 20 | ||
FL | 1 × 106 | 4 of 24 | 2.7 |
3 × 105 | 7 of 24 | (2.3-3.2) | |
1 × 105 | 17 of 24 |
Cells injected into mice . | No. cells injected per mouse . | Proportion of negative mice . | CRU frequency (per 106 cells) . |
---|---|---|---|
CB | 3 × 106 | 3 of 21 | 1.0 |
1 × 106 | 7 of 21 | (0.8-1.2)* | |
3 × 105 | 13 of 20 | ||
FL | 1 × 106 | 4 of 24 | 2.7 |
3 × 105 | 7 of 24 | (2.3-3.2) | |
1 × 105 | 17 of 24 |
CRU indicates competitive repopulating unit; CB, cord blood; FL, fetal liver.
Values shown in brackets are the range defined by the mean ± SEM and have been pooled from data obtained in 4 experiments with CB and 4 experiments with FL.