Summary of patient's laboratory data of blood coagulation and vitamin K-dependent proteins plasma levels
| . | Pt 30 (7 d) . | Pt 2 (18 mo) . | Pt 4 (7 d) . | Pt 4 (18 mo) . | Pt 4* (20 mo) . |
|---|---|---|---|---|---|
| PT (s) | 12 | 12 | >100 | >100 | 20.2 |
| PTT (s) | 30 | 32 | >100 | >100 | 36 |
| Fibrinogen g/L | 3.9 | 2.8 | 2.8 | 2.8 | 2.8 |
| Bleeding time (s) | 120 | 150 | 90 | — | — |
| Platelets (number) | 296 000 | 273 000 | 154 000 | 448 000 | 301 000 |
| Factor II (% normal) | 100 | 116 | — | 4.8 | 36 |
| Factor V (% normal) | 85 | 88 | 76.5 | 100 | — |
| Factor VII (% normal) | 62 | 90 | <1 | <1 | 30 |
| Factor VIII (% normal) | 100 | 80 | 100 | 100 | 100 |
| Factor IX (% normal) | 100 | 60 | 9 | 6.4 | 40 |
| Factor X (% normal) | 100 | 100 | 26 | <1 | 66 |
| Protein C (% normal) | 90 | 110 | — | — | 40 |
| Protein S (% normal) | 84 | 107 | — | — | 35 |
| UcOC (μg/L) | 5.5 | 4.4 | >9.4 | ||
| Vitamin K1(μg/L) | — | — | — | — | >1000 |
| Vitamin K1O (μg/L) | — | — | — | — | 0.38 |
| . | Pt 30 (7 d) . | Pt 2 (18 mo) . | Pt 4 (7 d) . | Pt 4 (18 mo) . | Pt 4* (20 mo) . |
|---|---|---|---|---|---|
| PT (s) | 12 | 12 | >100 | >100 | 20.2 |
| PTT (s) | 30 | 32 | >100 | >100 | 36 |
| Fibrinogen g/L | 3.9 | 2.8 | 2.8 | 2.8 | 2.8 |
| Bleeding time (s) | 120 | 150 | 90 | — | — |
| Platelets (number) | 296 000 | 273 000 | 154 000 | 448 000 | 301 000 |
| Factor II (% normal) | 100 | 116 | — | 4.8 | 36 |
| Factor V (% normal) | 85 | 88 | 76.5 | 100 | — |
| Factor VII (% normal) | 62 | 90 | <1 | <1 | 30 |
| Factor VIII (% normal) | 100 | 80 | 100 | 100 | 100 |
| Factor IX (% normal) | 100 | 60 | 9 | 6.4 | 40 |
| Factor X (% normal) | 100 | 100 | 26 | <1 | 66 |
| Protein C (% normal) | 90 | 110 | — | — | 40 |
| Protein S (% normal) | 84 | 107 | — | — | 35 |
| UcOC (μg/L) | 5.5 | 4.4 | >9.4 | ||
| Vitamin K1(μg/L) | — | — | — | — | >1000 |
| Vitamin K1O (μg/L) | — | — | — | — | 0.38 |
After 2 months oral vitamin K1 therapy (5 mg/d). All vitamin K-dependent protein plasma levels are expressed as percentage of normal pooled plasma.
PT, prothrombin time; PTT, partial thromboplastin time; UcOC, undercarboxylated osteocalcin.