Table 2.

Thrombopoietin serum levels in patients with congenital amegakaryocytic thrombocytopenia

Patient identificationAge (y)TPO serum level (pg/mL)TPO bioactivity
CAMT-1 0.3 nt 
CAMT-6 0.7 1606* nt  
CAMT-7 3.4 2653 
 6.5 3290* nt  
CAMT-8 2.2 2436* 
CAMT-9 2.3 nt +  
 3.0 2083* nt 
CAMT-11 7.8 3226* +  
CAMT-12 3.7 1022* nt 
CAMT-13 1.5 2674 +  
CAMT-17 1.8 1092 
Healthy donors (mean ± SD,
n = 40) 
 120 ± 76 − 
Patient identificationAge (y)TPO serum level (pg/mL)TPO bioactivity
CAMT-1 0.3 nt 
CAMT-6 0.7 1606* nt  
CAMT-7 3.4 2653 
 6.5 3290* nt  
CAMT-8 2.2 2436* 
CAMT-9 2.3 nt +  
 3.0 2083* nt 
CAMT-11 7.8 3226* +  
CAMT-12 3.7 1022* nt 
CAMT-13 1.5 2674 +  
CAMT-17 1.8 1092 
Healthy donors (mean ± SD,
n = 40) 
 120 ± 76 − 

nt = not tested.

*

Measured with R&D systems enzyme-linked immunosorbent assay (ELISA).

Measured with an ELISA system developed by Folman et al.9 

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