Characteristics of patients achieving remission on CCG-2891 (n = 537)
| . | Allogeneic BMT (n = 181) . | Autologous BMT (n = 177) . | Chemotherapy (n = 179) . | Total . | (%) . | P value for homogeneity . | |||
|---|---|---|---|---|---|---|---|---|---|
| No. . | (%) . | No. . | (%) . | No. . | (%) . | ||||
| Induction regimen | |||||||||
| Intensive | 113 | (64) | 115 | (66) | 108 | (61) | 336 | (64) | |
| Standard | 64 | (36) | 59 | (34) | 69 | (39) | 192 | (36) | .61 |
| Age, y | |||||||||
| 0-1 | 24 | (13) | 43 | (24) | 49 | (27) | 116 | (22) | |
| 2-10 | 78 | (43) | 68 | (38) | 62 | (35) | 208 | (39) | |
| 11-20 | 79 | (44) | 66 | (37) | 68 | (38) | 213 | (40) | .018 |
| White blood count (φL) | |||||||||
| Median | 18.000 | 22.250 | 21.300 | 20.900 | |||||
| Range | .500-351.200 | .500-532.800 | 1.100-345.800 | .500-532.800 | .15 | ||||
| FAB subtype | |||||||||
| M0 | 6 | (4) | 4 | (2) | 5 | (3) | 15 | (3) | |
| M1 | 28 | (17) | 25 | (15) | 31 | (18) | 84 | (16) | |
| M2 | 45 | (28) | 51 | (30) | 44 | (26) | 140 | (27) | |
| M3 | 10 | (6) | 9 | (5) | 11 | (6) | 30 | (6) | |
| M4 | 45 | (28) | 42 | (25) | 39 | (23) | 126 | (25) | |
| M5 | 22 | (14) | 28 | (16) | 31 | (18) | 81 | (16) | |
| M6 | 6 | (4) | 1 | (1) | 4 | (2) | 11 | (2) | |
| M7 | 10 | (6) | 11 | (6) | 5 | (3) | 26 | (5) | |
| Unknown | 9 | — | 6 | — | 9 | — | 24 | — | .77 |
| Cytogenetics | n = 79 | n = 83 | n = 77 | n = 239 | |||||
| Normal | 15 | (19) | 18 | (22) | 17 | (22) | 50 | (21) | .87 |
| 11q23 abnormality | 11 | (14) | 12 | (14) | 19 | (25) | 42 | (18) | .14 |
| t(8;21) | 15 | (19) | 12 | (14) | 5 | (6) | 32 | (13) | .07 |
| t(15;17) | 6 | (8) | 4 | (5) | 6 | (8) | 16 | (7) | .70 |
| 16q abnormality | 9 | (11) | 7 | (8) | 7 | (9) | 23 | (10) | .80 |
| +8 | 2 | (3) | 4 | (5) | 2 | (3) | 8 | (3) | .83 |
| -7/7q- | 3 | (4) | 0 | (0) | 2 | (3) | 5 | (2) | .22 |
| Other | 18 | (23) | 26 | (31) | 19 | (25) | 63 | (26) | |
| . | Allogeneic BMT (n = 181) . | Autologous BMT (n = 177) . | Chemotherapy (n = 179) . | Total . | (%) . | P value for homogeneity . | |||
|---|---|---|---|---|---|---|---|---|---|
| No. . | (%) . | No. . | (%) . | No. . | (%) . | ||||
| Induction regimen | |||||||||
| Intensive | 113 | (64) | 115 | (66) | 108 | (61) | 336 | (64) | |
| Standard | 64 | (36) | 59 | (34) | 69 | (39) | 192 | (36) | .61 |
| Age, y | |||||||||
| 0-1 | 24 | (13) | 43 | (24) | 49 | (27) | 116 | (22) | |
| 2-10 | 78 | (43) | 68 | (38) | 62 | (35) | 208 | (39) | |
| 11-20 | 79 | (44) | 66 | (37) | 68 | (38) | 213 | (40) | .018 |
| White blood count (φL) | |||||||||
| Median | 18.000 | 22.250 | 21.300 | 20.900 | |||||
| Range | .500-351.200 | .500-532.800 | 1.100-345.800 | .500-532.800 | .15 | ||||
| FAB subtype | |||||||||
| M0 | 6 | (4) | 4 | (2) | 5 | (3) | 15 | (3) | |
| M1 | 28 | (17) | 25 | (15) | 31 | (18) | 84 | (16) | |
| M2 | 45 | (28) | 51 | (30) | 44 | (26) | 140 | (27) | |
| M3 | 10 | (6) | 9 | (5) | 11 | (6) | 30 | (6) | |
| M4 | 45 | (28) | 42 | (25) | 39 | (23) | 126 | (25) | |
| M5 | 22 | (14) | 28 | (16) | 31 | (18) | 81 | (16) | |
| M6 | 6 | (4) | 1 | (1) | 4 | (2) | 11 | (2) | |
| M7 | 10 | (6) | 11 | (6) | 5 | (3) | 26 | (5) | |
| Unknown | 9 | — | 6 | — | 9 | — | 24 | — | .77 |
| Cytogenetics | n = 79 | n = 83 | n = 77 | n = 239 | |||||
| Normal | 15 | (19) | 18 | (22) | 17 | (22) | 50 | (21) | .87 |
| 11q23 abnormality | 11 | (14) | 12 | (14) | 19 | (25) | 42 | (18) | .14 |
| t(8;21) | 15 | (19) | 12 | (14) | 5 | (6) | 32 | (13) | .07 |
| t(15;17) | 6 | (8) | 4 | (5) | 6 | (8) | 16 | (7) | .70 |
| 16q abnormality | 9 | (11) | 7 | (8) | 7 | (9) | 23 | (10) | .80 |
| +8 | 2 | (3) | 4 | (5) | 2 | (3) | 8 | (3) | .83 |
| -7/7q- | 3 | (4) | 0 | (0) | 2 | (3) | 5 | (2) | .22 |
| Other | 18 | (23) | 26 | (31) | 19 | (25) | 63 | (26) | |