Table 4. Antithrombin III–induced... | American Society of Hematology

Table 4.

Antithrombin III–induced signaling mediating neutrophil chemotaxis

Pretreatment	Chemotaxis versus
Pretreatment	Medium	AT III [1 U]	IL-8 [1 nM]
Medium	1.000 ± 0.00	1.491 ± 0.06	1.718 ± 0.16
GFX [500 nM]	1.054 ± 0.09	1.192 ± 0.08^4-150	1.387 ± 0.10^4-150
Staurosporine [10 ng/mL]	0.980 ± 0.12	1.053 ± 0.10^4-150	1.181 ± 0.16^4-150
Tyrphostin [10 ng/mL]	1.105 ± 0.08	1.354 ± 0.04 ns	1.757 ± 0.11 ns
IBMX [100 μM]	1.113 ± 0.10	1.124 ± 0.07^4-150	1.212 ± 0.04^4-150
Wortmannin [10 nM]	0.965 ± 0.09	1.349 ± 0.07 ns	1.971 ± 0.17 ns

Pretreatment	Chemotaxis versus
Pretreatment	Medium	AT III [1 U]	IL-8 [1 nM]
Medium	1.000 ± 0.00	1.491 ± 0.06	1.718 ± 0.16
GFX [500 nM]	1.054 ± 0.09	1.192 ± 0.08^4-150	1.387 ± 0.10^4-150
Staurosporine [10 ng/mL]	0.980 ± 0.12	1.053 ± 0.10^4-150	1.181 ± 0.16^4-150
Tyrphostin [10 ng/mL]	1.105 ± 0.08	1.354 ± 0.04 ns	1.757 ± 0.11 ns
IBMX [100 μM]	1.113 ± 0.10	1.124 ± 0.07^4-150	1.212 ± 0.04^4-150
Wortmannin [10 nM]	0.965 ± 0.09	1.349 ± 0.07 ns	1.971 ± 0.17 ns

Mann-Whitney test after Kruskal-Wallis analysis of variance (P < .01); n = 6.

For abbreviations, see Table 2.

P < .05.