Table 3.

Allele frequencies and pairwise linkage disequilibrium coefficients between polymorphisms

PolymorphismAlleleAllele frequencies± D′
− 2345− 438aa147+ 1542+ 1583
−2599 C, G .51/.49 − 1.00 + 1.00 − 0.85 + 0.83 − 0.78 
− 2345 2G, 1G .69/.31  − 1.00 + 0.84 − 0.75 + 0.77 
−438 G, A .71/.29   − 1.00 + 0.85 − 0.75 
aa147 Ala, Thr .76/.24    − 0.86 + 0.95 
+ 1542 C, G .70/.30     − 0.92 
+ 1583 T, A .70/.30      
PolymorphismAlleleAllele frequencies± D′
− 2345− 438aa147+ 1542+ 1583
−2599 C, G .51/.49 − 1.00 + 1.00 − 0.85 + 0.83 − 0.78 
− 2345 2G, 1G .69/.31  − 1.00 + 0.84 − 0.75 + 0.77 
−438 G, A .71/.29   − 1.00 + 0.85 − 0.75 
aa147 Ala, Thr .76/.24    − 0.86 + 0.95 
+ 1542 C, G .70/.30     − 0.92 
+ 1583 T, A .70/.30      

All coefficients are significantly different from 0 (P < .001).

The A-1690G, G-1102T, and G-438A polymorphisms were in nearly complete concordance; thus, A-1690G and G-1102T are not reported in this table.

or Create an Account

Close Modal
Close Modal