Allele frequencies and pairwise linkage disequilibrium coefficients between polymorphisms
Polymorphism . | Allele . | Allele frequencies . | ± D′ . | ||||
---|---|---|---|---|---|---|---|
− 2345 . | − 438 . | aa147 . | + 1542 . | + 1583 . | |||
−2599 | C, G | .51/.49 | − 1.00 | + 1.00 | − 0.85 | + 0.83 | − 0.78 |
− 2345 | 2G, 1G | .69/.31 | − 1.00 | + 0.84 | − 0.75 | + 0.77 | |
−438 | G, A | .71/.29 | − 1.00 | + 0.85 | − 0.75 | ||
aa147 | Ala, Thr | .76/.24 | − 0.86 | + 0.95 | |||
+ 1542 | C, G | .70/.30 | − 0.92 | ||||
+ 1583 | T, A | .70/.30 |
Polymorphism . | Allele . | Allele frequencies . | ± D′ . | ||||
---|---|---|---|---|---|---|---|
− 2345 . | − 438 . | aa147 . | + 1542 . | + 1583 . | |||
−2599 | C, G | .51/.49 | − 1.00 | + 1.00 | − 0.85 | + 0.83 | − 0.78 |
− 2345 | 2G, 1G | .69/.31 | − 1.00 | + 0.84 | − 0.75 | + 0.77 | |
−438 | G, A | .71/.29 | − 1.00 | + 0.85 | − 0.75 | ||
aa147 | Ala, Thr | .76/.24 | − 0.86 | + 0.95 | |||
+ 1542 | C, G | .70/.30 | − 0.92 | ||||
+ 1583 | T, A | .70/.30 |
All coefficients are significantly different from 0 (P < .001).
The A-1690G, G-1102T, and G-438A polymorphisms were in nearly complete concordance; thus, A-1690G and G-1102T are not reported in this table.