Human and viral interleukin-6 in sera from patients with multicentric Castleman disease and/or primary effusion lymphoma
| Case no. . | HIV status . | MCD . | PEL . | Related diseases . | Time of 2nd/3rd sampling . | vIL-6 pg/mL . | hIL-6 pg/mL . | Anti-KSHV IgG OD ratio* . |
|---|---|---|---|---|---|---|---|---|
| 11 | + | + | − | — | — | < 300 | 11.6 | 8.23 |
| 2 days later | 1076 | 5.8 | 9.01 | |||||
| 13 days later | 2628 | 1964.4 | 9.63 | |||||
| 12 | + | + | − | KS | — | 5795 | < 1.0 | 6.24 |
| 13 | + | + | − | AIHA | — | < 300 | 43.4 | 6.38 |
| 14 | + | + | − | AIHA | — | 766 | 6096.7 | 2.36 |
| 10 days later | 2549 | 6432.8 | 2.38 | |||||
| 15 | + | + | + | — | — | < 300 | 18 113.0 | 10.62 |
| 40 days later | 17 804 | 134.0 | 9.87 | |||||
| 16 | + | − | + | NHL in CNS | — | < 300 | 54.9 | < 1.0 |
| 17 | + | − | + | — | — | 11 833 | < 1.0 | 8.49 |
| 7 months later | 448 | < 1.0 | 9.73 | |||||
| 18 | − | + | − | — | — | < 300 | 31.7 | < 1.0 |
| 19 | − | + | − | — | — | < 300 | 38.8 | < 1.0 |
| 20 | − | + | − | — | — | < 300 | < 1.0 | < 1.0 |
| 21 | − | + | − | — | — | < 300 | < 1.0 | < 1.0 |
| Case no. . | HIV status . | MCD . | PEL . | Related diseases . | Time of 2nd/3rd sampling . | vIL-6 pg/mL . | hIL-6 pg/mL . | Anti-KSHV IgG OD ratio* . |
|---|---|---|---|---|---|---|---|---|
| 11 | + | + | − | — | — | < 300 | 11.6 | 8.23 |
| 2 days later | 1076 | 5.8 | 9.01 | |||||
| 13 days later | 2628 | 1964.4 | 9.63 | |||||
| 12 | + | + | − | KS | — | 5795 | < 1.0 | 6.24 |
| 13 | + | + | − | AIHA | — | < 300 | 43.4 | 6.38 |
| 14 | + | + | − | AIHA | — | 766 | 6096.7 | 2.36 |
| 10 days later | 2549 | 6432.8 | 2.38 | |||||
| 15 | + | + | + | — | — | < 300 | 18 113.0 | 10.62 |
| 40 days later | 17 804 | 134.0 | 9.87 | |||||
| 16 | + | − | + | NHL in CNS | — | < 300 | 54.9 | < 1.0 |
| 17 | + | − | + | — | — | 11 833 | < 1.0 | 8.49 |
| 7 months later | 448 | < 1.0 | 9.73 | |||||
| 18 | − | + | − | — | — | < 300 | 31.7 | < 1.0 |
| 19 | − | + | − | — | — | < 300 | 38.8 | < 1.0 |
| 20 | − | + | − | — | — | < 300 | < 1.0 | < 1.0 |
| 21 | − | + | − | — | — | < 300 | < 1.0 | < 1.0 |
Samples with OD ratio 1.0 were interpreted as positive.
MCD indicates multicentric Castleman disease; PEL, primary effusion lymphoma; AIHA, autoimmune hemolytic anemia; NHL, non-Hodgkin lymphoma; CNS, central nervous system; for other abbreviations, see Table 1.