Correlation of clonotypic PCR results with bone marrow biopsy results at nPR
| Patient . | PCR result . | Disease assessment on bone marrow biopsy . |
|---|---|---|
| 2 | 100 | Few irregular clusters of small lymphocytes |
| 4 | 10−2/PB | Several aggregates of small, round lymphocytes |
| 7 | 10−5 | Single, minute cluster of small lymphocytes |
| 10 | Positive* | Two lymphoid follicles |
| 13 | Positive† | Irregular, dense clusters of small lymphoid cells |
| Patient . | PCR result . | Disease assessment on bone marrow biopsy . |
|---|---|---|
| 2 | 100 | Few irregular clusters of small lymphocytes |
| 4 | 10−2/PB | Several aggregates of small, round lymphocytes |
| 7 | 10−5 | Single, minute cluster of small lymphocytes |
| 10 | Positive* | Two lymphoid follicles |
| 13 | Positive† | Irregular, dense clusters of small lymphoid cells |
Results of PCR are presented as the minimum number of cells assayed by limiting-dilution analysis, which still yielded a positive PCR result on the semi-nested round of PCR.
Paraffin section used as source of DNA; only qualitative result available.
Bone marrow aspirate slide used as source of DNA; only qualitative result available.