Table 1.

Gene expression data from cDNA arrays

GeneAML specimensNormal specimens
1234567123
 CD34 
DAPK 
IRF-1 
AML-1 — 
AF-4 0.5 — — 
EWS — — 
Ikaros — 
STAT6 — — 
GeneAML specimensNormal specimens
1234567123
 CD34 
DAPK 
IRF-1 
AML-1 — 
AF-4 0.5 — — 
EWS — — 
Ikaros — 
STAT6 — — 

Table numbers reflect relative expression levels in comparison to CD34. AML specimens correspond to the following: 1 = French-American-British (FAB) M4, hyperdiploid (white blood count [WBC] = 80 K, 99% CD123+); 2 = FAB M2, normal karyotype (WBC = >200 K, 99% CD123+); 3 = FAB M1, karyotype not determined (WBC = 130 K, 100% CD123+); 4 = FAB M2/M6, monosomy 7 (WBC = 86 K, 95% CD123+); 5 = FAB M4, normal karyotype (WBC = >100 K, 99% CD123+); 6 = FAB M1, normal karyotype (WBC = 140 K, 97% CD123+); 7 = FAB M4, normal karyotype (WBC = >100 K, 98% CD123+). All samples were derived from sorted CD34+/CD38 cells. Bone marrow specimens were derived from normal donors.

AML indicates acute myelogenous leukemia; DAPK, death-associated protein kinase; and IRF, interferon regulatory factor.

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