Statistical comparison of on-drug versus off-drug values
| . | CECs with positive expression, mean ± SD, % . | P . | |
|---|---|---|---|
| Off drug . | On drug . | ||
| Sulfasalazine trial | |||
| Patient A | |||
| E-selection | 73 ± 17 | 30 ± 5 | <.001 |
| ICAM-1 | 64 ± 13 | 36 ± 10 | <.001 |
| VCAM-1 | 66 ± 20 | 28 ± 10 | .001 |
| Tissue factor | 78 ± 16 | 66 ± 9 | NS |
| Patient B | |||
| E-selection | 64 ± 12 | 36 ± 15 | <.001 |
| ICAM-1 | 77 ± 12 | 52 ± 21 | .001 |
| VCAM-1 | 73 ± 10 | 42 ± 16 | <.001 |
| Tissue factor | 84 ± 9 | 73 ± 15 | NS |
| Patient C | |||
| E-selection | 71 ± 21 | 29 ± 12 | .009 |
| ICAM-1 | 66 ± 10 | 33 ± 11 | .01 |
| VCAM-1 | 63 ± 11 | 31 ± 27 | .017 |
| Tissue factor | 69 ± 11 | 63 ± 4 | NS |
| Placebo trial | |||
| Patient A | |||
| E-selection | 85 ± 17 | 84 ± 16 | NS |
| ICAM-1 | 66 ± 5 | 68 ± 10 | NS |
| VCAM-1 | 69 ± 15 | 62 ± 8 | NS |
| Tissue factor | 75 ± 6 | 76 ± 6 | NS |
| . | CECs with positive expression, mean ± SD, % . | P . | |
|---|---|---|---|
| Off drug . | On drug . | ||
| Sulfasalazine trial | |||
| Patient A | |||
| E-selection | 73 ± 17 | 30 ± 5 | <.001 |
| ICAM-1 | 64 ± 13 | 36 ± 10 | <.001 |
| VCAM-1 | 66 ± 20 | 28 ± 10 | .001 |
| Tissue factor | 78 ± 16 | 66 ± 9 | NS |
| Patient B | |||
| E-selection | 64 ± 12 | 36 ± 15 | <.001 |
| ICAM-1 | 77 ± 12 | 52 ± 21 | .001 |
| VCAM-1 | 73 ± 10 | 42 ± 16 | <.001 |
| Tissue factor | 84 ± 9 | 73 ± 15 | NS |
| Patient C | |||
| E-selection | 71 ± 21 | 29 ± 12 | .009 |
| ICAM-1 | 66 ± 10 | 33 ± 11 | .01 |
| VCAM-1 | 63 ± 11 | 31 ± 27 | .017 |
| Tissue factor | 69 ± 11 | 63 ± 4 | NS |
| Placebo trial | |||
| Patient A | |||
| E-selection | 85 ± 17 | 84 ± 16 | NS |
| ICAM-1 | 66 ± 5 | 68 ± 10 | NS |
| VCAM-1 | 69 ± 15 | 62 ± 8 | NS |
| Tissue factor | 75 ± 6 | 76 ± 6 | NS |
Data shown as mean ± SD for data depicted in Figure 2. The nominal P value indicated is explained in “Materials and methods.” NS indicates not significant.