The effects of different VE-cadherin antibodies on endothelial cell activities
| mAbs . | Permeability . | Ca++switch . | Apoptosis . | Tube formation . | Domain . |
|---|---|---|---|---|---|
| Cad 5 | +++ | +++ | +++ | +++ | EC1 |
| BV9 | ++ | +++ | +++ | +++ | EC3-EC4 |
| BV6 | ++ | ++ | ++ | +++ | EC3 |
| TEA 1.31 | + | + | + | − | EC3-EC4 |
| Hec 1.2 | − | − | − | − | EC3-EC4 |
| mAbs . | Permeability . | Ca++switch . | Apoptosis . | Tube formation . | Domain . |
|---|---|---|---|---|---|
| Cad 5 | +++ | +++ | +++ | +++ | EC1 |
| BV9 | ++ | +++ | +++ | +++ | EC3-EC4 |
| BV6 | ++ | ++ | ++ | +++ | EC3 |
| TEA 1.31 | + | + | + | − | EC3-EC4 |
| Hec 1.2 | − | − | − | − | EC3-EC4 |
− indicates no effect; +, barely detectable; ++, intermediate; +++, strong activity. For the actual data see the corresponding figures.